Improvements in blood pressure among undiagnosed hypertensive participants in a community-based lifestyle intervention, Mississippi, 2010.

Improvements in blood pressure among undiagnosed hypertensive participants in a community-based lifestyle intervention, Mississippi, 2010.
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DOI:
10.5888/pcd11.130269
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发表时间:
2014-04-04
影响因子:
5.5
通讯作者:
Yadrick K
Yadrick K
中科院分区:
医学3区
文献类型:
--
作者:
Zoellner J;Thomson JL;Landry AS;Anderson-Lewis C;Connell C;Molaison EF;Yadrick K

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需要有效的策略来接触和治疗那些缺乏高血压意识或高血压未得到控制的人。我们使用基于社区的参与性研究计划 Hub City Steps 的数据来量化未确诊高血压的患病率,并确定基线高血压状况与干预后血压和健康相关生活质量改善之间的关系。 Hub City Steps 是针对高血压危险因素的为期 6 个月的干预前-干预后生活方式干预。在基线、3 个月和 6 个月时收集结果指标。使用广义线性混合模型来测试时间和高血压状态的影响。在登记样本 (N = 269) 中,大多数是超重或肥胖 (91%)、非洲裔美国人 (94%) 和女性 (85%)。在考虑高血压状况时,42% 的人自我报告诊断为高血压(自我报告亚组;84% 使用抗高血压药物); 36%的人没有自我报告的高血压病史,但在测量血压时,他们被临床诊断为高血压前期或高血压(未诊断亚组); 22% 的人没有自我报告或临床高血压诊断(无高血压亚组)。从基线到 6 个月,自我报告高血压 [8.2 (SD, 18.2) mm Hg] 和未诊断高血压 [12.3 (SD, 16.3) mm Hg] 的参与者的收缩压显着改善,其中未诊断参与者的改善最大 (P < .001)。控制协变量后,效果仍然显着。所有 3 个高血压亚组的健康相关生活质量均显着改善,且没有明显的亚组差异。这项研究揭示了文化上适当的基于社区的参与性研究计划的优势,该计划可以帮助那些未被发现的高血压患者,并有效改善血压状况和健康相关的生活质量。
Effective strategies are needed to reach and treat people who lack awareness of or have uncontrolled hypertension. We used data from a community-based participatory research initiative, Hub City Steps, to quantify the prevalence of undiagnosed hypertension and determine the relationship between hypertension status at baseline and postintervention improvements in blood pressure and health-related quality of life. Hub City Steps was a 6-month preintervention–postintervention lifestyle intervention targeting hypertension risk factors. Outcome measures were collected at baseline, 3 months, and 6 months. Generalized linear mixed models were used to test for effects by time and hypertension status. Of the enrolled sample (N = 269), most were overweight or obese (91%), African American (94%), and women (85%). When considering hypertension status, 42% had self-reported diagnosis of hypertension (self-reported subgroup; 84% with antihypertensive medication use); 36% had no self-reported medical history of hypertension, but when blood pressure was measured they had a clinical diagnosis of prehypertension or hypertension (undiagnosed subgroup); and 22% had no self-reported or clinical hypertension diagnosis (no hypertension subgroup). From baseline to 6 months, systolic blood pressure significantly improved for participants with self-reported hypertension [8.2 (SD, 18.2) mm Hg] and undiagnosed hypertension [12.3 (SD, 16.3) mm Hg], with undiagnosed participants experiencing the greatest improvements (P < .001). Effects remained significant after controlling for covariates. Health-related quality of life significantly improved for all 3 hypertension subgroups, with no apparent subgroup differences. This study reveals advantages of a culturally appropriate community-based participatory research initiative to reach those with undetected hypertension and effectively improve blood pressure status and health-related quality of life.
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