Scapular osteochondrolipoma: Imaging features with pathological correlation.

Scapular osteochondrolipoma: Imaging features with pathological correlation.
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DOI:
10.3892/ol.2013.1455
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发表时间:
2013-09
期刊:
影响因子:
2.9
通讯作者:
Naito M
Naito M
中科院分区:
医学4区
文献类型:
--
作者:
Nishio J;Ideta S;Iwasaki H;Naito M

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骨软骨脂肪瘤是一种极为罕见的脂肪瘤的组织学变异,骨性和软骨分化。本研究报告一个不寻常的情况下,骨软骨脂肪瘤发生在左肩胛骨区域的49岁男性。体格检查发现一个3厘米,坚硬,无压痛和最小移动肿块。x线平片显示轻度骨化软组织肿块,无骨侵蚀迹象。计算机断层扫描(CT)证实了病变的存在和肩胛骨的正常外观。磁共振成像(MRI)显示一个边界清晰的皮下肿块,在T1和t2加权序列上具有几乎均匀的高信号强度。对比增强脂肪抑制t1加权序列显示肿块周围和间隔微弱强化。对肿瘤进行边缘切除。组织学上,肿瘤主要由成熟脂肪细胞和成熟骨的薄小梁混合组成。此外,在病变周围发现少量成熟的透明软骨和类骨。基于这些发现,肿瘤被诊断为骨软骨脂肪瘤。患者随访6个月无局部复发迹象。尽管罕见,骨软骨脂肪瘤应被视为肩胛骨区一种明确的、钙化/骨化的皮下肿块的鉴别诊断。
Osteochondrolipoma is an extremely rare histological variant of lipoma with osseous and cartilaginous differentiation. The present study reports an unusual case of an osteochondrolipoma occurring in the left scapular region of a 49-year-old male. The physical examination revealed a 3-cm, hard, non-tender and minimally mobile mass. Plain radiography revealed a faintly ossified soft-tissue mass without evidence of bone erosion. Computed tomography (CT) confirmed the presence of a lesion and the normal appearance of the scapula. Magnetic resonance imaging (MRI) showed a well-circumscribed subcutaneous mass with an almost homogeneous high signal intensity on the T1- and T2-weighted sequences. Contrast-enhanced fat-suppressed T1-weighted sequences demonstrated a faint peripheral and septal enhancement of the mass. A marginal excision of the tumor was performed. Histologically, the tumor was predominantly composed of mature adipocytes mixed with thin trabeculae of mature bone. In addition, small amounts of mature hyaline cartilage and osteoid were identified in the periphery of the lesion. Based on these findings, the tumor was diagnosed as an osteochondrolipoma. The patient demonstrated no evidence of local recurrence within six months of follow-up. Although rare, osteochondrolipoma should be considered as a differential diagnosis of a well-defined, calcified/ossified, subcutaneous mass in the scapular region.
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