The impaired healing hypothesis: a mechanism by which psychosocial stress and personal characteristics increase MSD risk?
The impaired healing hypothesis: a mechanism by which psychosocial stress and personal characteristics increase MSD risk?
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DOI：
10.1080/00140139.2021.1974103
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发表时间：
2022-04
期刊：
影响因子：
2.4
通讯作者：
Barbe, Mary F.
中科院分区：
文献类型：
--
作者：
Gallagher, Sean;Barbe, Mary F.
虽然身体风险因素对MSD发展的影响一直是肌肉骨骼研究的主要焦点，但心理压力源和某些个人特征（例如，年龄、性别和肥胖）也与MSD风险增加相关。以上列出的心理和个人特征有一个共同的特点：所有这些都与身体神经内分泌和免疫反应的破坏有关，导致愈合过程受损。受损的愈合反应可能会导致肌肉骨骼组织的疲劳寿命缩短，这是由于与累积损伤（通常可修复）保持同步的能力降低，以及由于延长的愈合过程，受损组织对进一步创伤的脆弱性增加。对工程自修复材料的研究表明，在机械载荷存在下，愈合动力学的降低会大大降低材料的疲劳寿命。提出了一个损伤累积和愈合的影响因素模型。
While the effects of physical risk factors on MSD development have been a primary focus of musculoskeletal research, psychological stressors and certain personal characteristics (e.g., aging, sex, and obesity) are also associated with increased MSD risk. The psychological and personal characteristics listed above share a common characteristic: all are associated with disruption of the body’s neuroendocrine and immune responses resulting in an impaired healing process. An impaired healing response may result in reduced fatigue life of musculoskeletal tissues due to a diminished ability to keep pace with accumulating damage (ordinarily reparable), and an increased vulnerability of damaged tissue to further trauma owing to the prolonged healing process. Research in engineered self-healing materials suggests that decreased healing kinetics in the presence of mechanical loading can substantially reduce the fatigue life of materials. A model of factors influencing damage accrual and healing is presented.
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影响因子：
2.4
作者：
Fung, David T.;Wang, Vincent M.;Andarawis-Puri, Nelly;Basta-Pljakic, Jelena;Li, Yonghui;Laudier, Damien M.;Sun, Hui B.;Jepsen, Karl J.;Schaffler, Mitchell B.;Flatow, Evan L.
通讯作者：
Flatow, Evan L.
影响因子：
2.4
作者：
Bani Hani, Dania;Rong, Huangfu;Gallagher, Sean
通讯作者：
Gallagher, Sean
影响因子：
4
作者：
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通讯作者：
Bedynska, Sylwia
DOI：
10.1302/0301-620x.60b2.659472
发表时间：
1978-01-01
影响因子：
--
作者：
CYRON, BM;HUTTON, WC
通讯作者：
HUTTON, WC
影响因子：
4.7
作者：
Eriksen, W
通讯作者：
Eriksen, W