Glycemic variability and cardiovascular disease in patients with type 2 diabetes.
Glycemic variability and cardiovascular disease in patients with type 2 diabetes.
复制标题
2型糖尿病患者的血糖变异性与心血管疾病
DOI：
10.1136/bmjdrc-2020-002032
复制
发表时间：
2021-03
影响因子：
4.1
通讯作者：
Umpierrez GE
中科院分区：
文献类型：
--
作者：
Martinez M;Santamarina J;Pavesi A;Musso C;Umpierrez GE
糖化血红蛋白是目前评估糖尿病患者长期血糖控制和药物治疗反应的金标准。然而，糖化血红蛋白不能解决血糖波动问题。血糖变异性（GV）是指血糖水平的波动。最近的临床数据表明，GV与糖尿病患者低血糖、微血管和大血管并发症以及死亡率的风险增加相关，与糖化血红蛋白水平无关。动态血糖监测设备的使用显著改善了临床实践中GV的评估，并促进了糖尿病患者GV以及低血糖和高血糖事件的评估。我们回顾了目前关于GV的定义和评估及其与2型糖尿病患者心血管并发症的关系的概念。
Glycated hemoglobin is currently the gold standard for assessment of long-term glycemic control and response to medical treatment in patients with diabetes. Glycated hemoglobin, however, does not address fluctuations in blood glucose. Glycemic variability (GV) refers to fluctuations in blood glucose levels. Recent clinical data indicate that GV is associated with increased risk of hypoglycemia, microvascular and macrovascular complications, and mortality in patients with diabetes, independently of glycated hemoglobin level. The use of continuous glucose monitoring devices has markedly improved the assessment of GV in clinical practice and facilitated the assessment of GV as well as hypoglycemia and hyperglycemia events in patients with diabetes. We review current concepts on the definition and assessment of GV and its association with cardiovascular complications in patients with type 2 diabetes.
登录
查看更多内容
影响因子：
16.2
作者：
Danne T;Nimri R;Battelino T;Bergenstal RM;Close KL;DeVries JH;Garg S;Heinemann L;Hirsch I;Amiel SA;Beck R;Bosi E;Buckingham B;Cobelli C;Dassau E;Doyle FJ 3rd;Heller S;Hovorka R;Jia W;Jones T;Kordonouri O;Kovatchev B;Kowalski A;Laffel L;Maahs D;Murphy HR;Nørgaard K;Parkin CG;Renard E;Saboo B;Scharf M;Tamborlane WV;Weinzimer SA;Phillip M
通讯作者：
Phillip M
影响因子：
16.2
作者：
通讯作者：
--
影响因子：
16.2
作者：
Agiostratidou, Gina;Anhalt, Henry;Weinzimer, Stuart A.
通讯作者：
Weinzimer, Stuart A.
影响因子：
158.5
作者：
Duckworth, William;Abraira, Carlos;Huang, Grant D.
通讯作者：
Huang, Grant D.
影响因子：
4.1
作者：
Kaze AD;Santhanam P;Erqou S;Ahima RS;Echouffo-Tcheugui JB
通讯作者：
Echouffo-Tcheugui JB