Common mental disorders in TB/HIV co-infected patients in Ethiopia.
Common mental disorders in TB/HIV co-infected patients in Ethiopia.
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DOI：
10.1186/1471-2334-10-201
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发表时间：
2010-07-09
影响因子：
3.7
通讯作者：
Colebunders R
中科院分区：
文献类型：
--
作者：
Deribew A;Tesfaye M;Hailmichael Y;Apers L;Abebe G;Duchateau L;Colebunders R
结核病/艾滋病病毒合并感染与常见精神障碍（CMD）之间的关系几乎没有调查。在这项研究中，我们比较了埃塞俄比亚结核病/艾滋病病毒合并感染和非合并感染艾滋病病毒患者中CMD的发生率。我们在2009年2月至4月在埃塞俄比亚的三家医院进行了一项横断面研究。研究人群包括155名TB/HIV合并感染者和465名非合并感染的HIV患者。CMD通过面对面的访谈，由训练有素的临床护士使用Kessler 10量表进行评估。使用结构化问卷评估了CMD的几个风险因素。TB/HIV合并感染患者的CMD风险（63.7%）显著（p = 0.001）高于非合并感染患者（46.7%）。当调整潜在混杂变量的影响时，TB/HIV合并感染者发生CMD的几率是非合并感染者的1.7倍[OR = 1.7，（95%CI：1.0，2.9）]。无收入来源的个体[OR = 1.7，（95%CI：1.1，2.8）]和日工[OR = 2.4，95%CI：1.2，5.1）]分别比有收入来源的个体和政府雇员更容易患CMD。认为耻辱感[OR = 2.2，95%CI：1.5，3.2）]和认为自己的总体健康状况“差”[OR = 10.0，95%CI：2.8，35.1）]的患者发生CMD的风险显著高于未认为耻辱感或认为自己的总体健康状况“好”的患者。结核病/艾滋病控制项目应制定指南，以筛查和治疗结核病/艾滋病合并感染患者中的CMD。筛查项目应侧重于没有收入来源的个人、失业者和日工。
The relationship between TB/HIV co-infection and common mental disorders (CMD) has been scarcely investigated. In this study, we compared the occurrence of CMD in TB/HIV co-infected and non-co-infected HIV patients in Ethiopia. We conducted a cross sectional study in three hospitals in Ethiopia from February to April, 2009. The study population consisted of 155 TB/HIV co-infected and 465 non-co-infected HIV patients. CMD was assessed through face to face interviews by trained clinical nurses using the Kessler 10 scale. Several risk factors for CMD were assessed using a structured questionnaire. TB/HIV co-infected patients had significantly (p = 0.001) greater risk of CMD (63.7%) than the non-co-infected patients (46.7%). When adjusted for the effect of potential confounding variables, the odds of having CMD for TB/HIV co-infected individuals was 1.7 times the odds for non-co-infected patients [OR = 1.7, (95%CI: 1.0, 2.9)]. Individuals who had no source of income [OR = 1.7, (95%CI: 1.1, 2.8)], and day labourers [OR = 2.4, 95%CI: 1.2, 5.1)] were more likely to have CMD as compared to individuals who had a source of income and government employees respectively. Patients who perceived stigma [OR = 2.2, 95%CI: 1.5, 3.2)] and who rate their general health as "poor" [OR = 10.0, 95%CI: 2.8, 35.1)] had significantly greater risk of CMD than individual who did not perceive stigma or who perceived their general health to be "good". TB/HIV control programs should develop guidelines to screen and treat CMD among TB/HIV co-infected patients. Screening programs should focus on individuals with no source of income, jobless people and day labourers.
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