HIV transmission: time for translational studies to bridge the gap.

HIV transmission: time for translational studies to bridge the gap.
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DOI:
10.1126/scitranslmed.3002329
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发表时间:
2011-04-06
影响因子:
17.1
通讯作者:
Herold BC
Herold BC
中科院分区:
医学1区
文献类型:
--
作者:
Anton P;Herold BC

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More than 7000 new HIV infections are documented each day worldwide. In this Perspective, we dissect new results from a large clinical trial showing that genital and plasma HIV-1 RNA loads predict the risk of heterosexual transmission and that genital tract viral RNA load does so independently of plasma viral load. Furthermore, beyond its defined study end points, this well-conducted trial identified new research directions that should be pursued in smaller intensive basic and translational studies.
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