Electrogastrography: physiological basis and clinical application in diabetic gastropathy.

Electrogastrography: physiological basis and clinical application in diabetic gastropathy.
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胃电图:糖尿病胃病的生理基础和临床应用。

DOI:
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发表时间:
2001
影响因子:
5.4
通讯作者:
Kenneth L. Koch
Kenneth L. Koch
中科院分区:
医学3区
文献类型:
--
作者:
Kenneth L. Koch

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胃电是通过放置在上腹部表面的电极记录和测量胃的肌电活动。正常胃电(EGG)反映由特殊起搏细胞(Cajal间质细胞)产生的3个每分钟循环(CPM)的胃肌电活动,Cajal间质细胞位于胃体和胃窦的肌壁。胃电节律失常(胃过速和胃动过缓)是正常胃起搏电位的紊乱,与恶心、上腹胀、腹胀、高血糖和胃排空延迟等症状有关。在糖尿病胃病中,正常的3-CPM电节律被胃动过缓、胃动过速和混合性或非特异性心律失常所取代。胃电节律紊乱的诊断确定了具有上胃肠道症状的糖尿病患者的客观神经肌肉异常。纠正胃电节律紊乱可以减少上消化道症状,并可能改善胃排空,所有这些都可能加强血糖控制。胃电地形图对胃电节律紊乱的诊断提供了对胃神经肌肉异常的新见解,并指导治疗以改善糖尿病患者的上消化道症状。
Electrogastrography is the recording and measurement of gastric myoelectrical activity from electrodes placed on the surface of the epigastrium. Normal electrogastrograms (EGGs) reflect 3 cycles per min (cpm) gastric myoelectrical activity produced by specialized pacemaker cells, the interstitial cells of Cajal, located in the muscular wall of the gastric corpus and antrum. Gastric dysrhythmias (tachygastrias and bradygastrias) are disturbances of the normal gastric pacesetter potentials and are associated with symptoms of nausea, epigastric fullness, and bloating and with hyperglycemia and delayed gastric emptying. In diabetic gastropathy, the normal 3-cpm electrical rhythm is replaced with bradygastrias, tachygastrias, and mixed or nonspecific dysrhythmias. Diagnosis of gastric dysrhythmias identifies an objective neuromuscular abnormality in diabetic patients with upper gastrointestinal (GI) symptoms. Correction of gastric dysrhythmias decreases upper GI symptoms and may improve gastric emptying all of which may enhance glucose control. The EGG diagnosis of gastric dysrhythmias provides new insights into gastric neuromuscular abnormalities and guides therapies to improve upper GI symptoms in patients with diabetes mellitus.
DOI: 10.2337/diabetes.49.10.1731
发表时间: 2000-10-01
期刊: DIABETES
影响因子: 7.7
作者:
Ördög, T;Takayama, I;Sanders, KM
通讯作者: Sanders, KM
使用[13C]辛酸呼气试验对有症状的糖尿病患者进行基于办公室的胃排空测量。
DOI: 10.1111/j.1572-0241.2000.03183.x
发表时间: 2000
期刊: The American journal of gastroenterology
影响因子: --
作者:
Lee,JS;Camilleri,M;Zinsmeister,AR;Burton,DD;Choi,MG;Nair,KS;Verlinden,M
通讯作者: Verlinden,M
DOI: 10.1016/0016-5085(86)90262-3
发表时间: 1986-06-01
期刊: GASTROENTEROLOGY
影响因子: 29.4
作者:
MEARIN, F;CAMILLERI, M;MALAGELADA, JR
通讯作者: MALAGELADA, JR