Stereotactic drainage of Aspergillus brain abscess with long-term survival: case report and review.

Aspergillus species are second only to Cryptococcus neoformans as the most common cause of fungal infections of the central nervous system in immunocompromised patients. Survival following treatment of Aspergillus brain abscess has been reported only 4 times. In each case, craniotomy was performed for abscess drainage. We present a case of long-term survival following stereotactic drainage of a bilateral Aspergillus brain abscess. In all reported cases, including the present one, histological examination of the abscess contents established the correct diagnosis. Amphotericin B was used in combination with operation in 4 of the 5 cases of long-term survival.

在免疫功能低下的患者中，曲霉菌属是中枢神经系统真菌感染的第二大常见病因，仅次于新型隐球菌。曲霉菌性脑脓肿经治疗后存活的病例仅报道过4例。在每一例中，都进行了开颅手术以引流脓肿。我们介绍了一例双侧曲霉菌性脑脓肿经立体定向引流后长期存活的病例。在包括本病例在内的所有报道病例中，对脓肿内容物的组织学检查确立了正确的诊断。在5例长期存活的病例中，有4例在手术的同时使用了两性霉素B。