Loneliness is associated with risk of cognitive impairment in the Survey of Health, Ageing and Retirement in Europe.
Loneliness is associated with risk of cognitive impairment in the Survey of Health, Ageing and Retirement in Europe.
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DOI：
10.1002/gps.5304
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发表时间：
2020-07
影响因子：
4
通讯作者：
Sutin AR
中科院分区：
文献类型：
--
作者：
Luchetti M;Terracciano A;Aschwanden D;Lee JH;Stephan Y;Sutin AR
在欧洲中年和老年人样本中，测试孤独是否与长达11年的认知障碍风险相关。该研究考察了这种联系是否独立于社会孤立，抑郁和其他认知障碍和痴呆症的风险因素。来自欧洲健康，老龄化和退休调查（SHARE）的参与者（N = 14，114）在基线时回答了一个关于孤独的项目，并每隔两到三年进行一次认知障碍评估，持续11年。在记忆回忆任务和语言流畅性任务中得分低于年龄分级平均值至少1.5个标准差的参与者被归类为受损。一个3项措施的孤独感可用于样本的受访者随访4年。在考虑了年龄、性别、教育程度和SHARE国家分层后，孤独感与偶发性认知障碍的风险增加相关（HR = 1.31，95%CI = 1.19-1.44）。这种关联是稳健的，但在控制临床和行为风险因素、健康相关活动限制、社交孤立、社交脱离和抑郁症状时，其程度有所降低。这种关联不受社会人口统计学因素的调节，并且在使用3项孤独量表而不是单项测量时也很明显。这些发现扩展了有关老年孤独和认知障碍风险的现有文献。孤独症是一个可改变的因素，可以在发生严重损害或痴呆之前进行干预。
To test whether loneliness is associated with risk of cognitive impairment up to 11 years later in a European sample of middle-aged and older adults. The study examines whether this association is independent of measures of social isolation, depression and other risk factors for cognitive impairment and dementia. Participants (N = 14,114) from the Survey of Health, Ageing and Retirement in Europe (SHARE) answered a single item on loneliness at baseline and were assessed for cognitive impairment every two-to-three years for 11 years. Participants who scored at least 1.5 standard deviations below the age-graded mean on both a memory recall task and verbal fluency task were classified as impaired. A 3-item measure of loneliness was available for a sample of respondents followed up to 4 years. Feeling lonely was associated with increased risk of incident cognitive impairment (HR = 1.31, 95%CI = 1.19–1.44), after accounting for age, sex, education, and SHARE country strata. The association was robust but reduced in magnitude when controlling for clinical and behavioral risk factors, health-related activity limitations, social isolation, social disengagement and depressive symptoms. The association was not moderated by socio-demographic factors and was also apparent when using the 3-item loneliness scale instead of the single-item measure. These findings expand the extant literature on loneliness and risk of cognitive impairment in older adulthood. Loneliness is one modifiable factor that can be intervened on prior to the development of severe impairment or dementia.
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影响因子：
4.2
作者：
Hawkley, Louise C.;Thisted, Ronald A.;Cacioppo, John T.
通讯作者：
Cacioppo, John T.
影响因子：
6.6
作者：
Peerenboom, L.;Collard, R. M.;Comijs, H. C.
通讯作者：
Comijs, H. C.
影响因子：
2.6
作者：
Hughes, ME;Waite, LJ;Cacioppo, JT
通讯作者：
Cacioppo, JT
影响因子：
2.7
作者：
Fokkema, Tineke;Gierveld, Jenny De Jong;Dykstra, Pearl A.
通讯作者：
Dykstra, Pearl A.
影响因子：
11
作者：
Holwerda, Tjalling Jan;Deeg, Dorly J. H.;Schoevers, Robert A.
通讯作者：
Schoevers, Robert A.