Evaluation, Treatment, and Impact of Neurologic Injury in Adult Patients on Extracorporeal Membrane Oxygenation: a Review.
Evaluation, Treatment, and Impact of Neurologic Injury in Adult Patients on Extracorporeal Membrane Oxygenation: a Review.
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DOI：
10.1007/s11940-021-00671-7
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发表时间：
2021
影响因子：
2
通讯作者：
LaBuzetta JN
中科院分区：
文献类型：
--
作者：
Illum B;Odish M;Minokadeh A;Yi C;Owens RL;Pollema T;LaBuzetta JN
体外膜氧（ECMO）越来越多地被用作心脏和呼吸衰竭的高级生命支持形式。不幸的是，在极少数情况下，循环和/或呼吸恢复被可能发生在需要ECMO的患者身上的神经损伤所掩盖。因此，ECMO的知识及其对神经损伤诊断和治疗的影响对重症医师和神经专家来说是不可或缺的。最常见的神经系统损伤包括脑出血、缺血性中风、癫痫发作、脑水肿、颅内高压、全脑缺氧/缺氧和脑死亡。这些是由ECMO开始前的事件、ECMO未能提供足够的氧气输送和/或ECMO期间发生的并发症引起的。ECMO幸存者也会经历与其他危重疾病幸存者相似的神经和心理后遗症。由于许多神经损伤的危险因素不能轻易减轻，早期诊断和干预对于限制ECMO期间神经损伤的发病率和死亡率至关重要。
Extracorporeal membrane oxygen (ECMO) is increasingly used as an advanced form of life support for cardiac and respiratory failure. Unfortunately, in infrequent instances, circulatory and/or respiratory recovery is overshadowed by neurologic injury that can occur in patients who require ECMO. As such, knowledge of ECMO and its implications on diagnosis and treatment of neurologic injuries is indispensable for intensivists and neurospecialists. The most common neurologic injuries include intracerebral hemorrhage, ischemic stroke, seizure, cerebral edema, intracranial hypertension, global cerebral hypoxia/anoxia, and brain death. These result from events prior to initiation of ECMO, failure of ECMO to provide adequate oxygen delivery, and/or complications that occur during ECMO. ECMO survivors also experience neurological and psychological sequelae similar to other survivors of critical illness. Since many of the risk factors for neurologic injury cannot be easily mitigated, early diagnosis and intervention are crucial to limit morbidity and mortality from neurologic injury during ECMO.
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影响因子：
1.9
作者：
Dehghani H;White BR;Zeff BW;Tizzard A;Culver JP
通讯作者：
Culver JP
DOI：
10.1038/sj.jp.7210593
发表时间：
2001-10-01
期刊：
Journal of perinatology : official journal of the California Perinatal Association
影响因子：
--
作者：
Gannon, C M;Kornhauser, M S;Spitzer, A R
通讯作者：
Spitzer, A R
影响因子：
3.4
作者：
Kasirajan, V;Smedira, NG;McCarthy, PM
通讯作者：
McCarthy, PM
影响因子：
4.7
作者：
Claassen, J;Hirsch, LJ;Mayer, SA
通讯作者：
Mayer, SA
影响因子：
3.4
作者：
Fletcher-Sandersjöö A;Thelin EP;Bartek J Jr;Broman M;Sallisalmi M;Elmi-Terander A;Bellander BM
通讯作者：
Bellander BM