Corrosion performances in simulated body fluids and cytotoxicity evaluation of Fe-based bulk metallic glasses
Corrosion performances in simulated body fluids and cytotoxicity evaluation of Fe-based bulk metallic glasses
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铁基大块金属玻璃的模拟体液腐蚀性能及细胞毒性评价
DOI：
10.1016/j.msec.2011.12.018
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发表时间：
2012-04
期刊：
影响因子：
--
通讯作者：
M. Li
中科院分区：
文献类型：
--
作者：
Y.F. Zheng;H.F. Li;Y.B. Wang;M. Li
通过电化学测试和间接接触细胞毒性试验，研究了Fe41Co7Cr15Mo14C15B6Y2(BMG1)、(Fe44Cr5Co5Mo13Mn11C16B6)98Y2(BMG2)和Fe48Cr15Mo14C15B6Er2(BMG3)三种铁基大块金属玻璃的耐蚀性和生物相容性。与316L不锈钢生物医用钢相比，铁基BMG在模拟体液(Hank‘s液和人工唾液)中表现出更好的耐蚀性。OCP曲线表明，铁基BMG表面的钝化膜非常稳定，类似于316L不锈钢。从阳极极化曲线得到的腐蚀电流密度从低到高依次为：BMG3<；BMG1<；BMG2<；316LSS。交流阻抗谱分析表明，除BMG2外，铁基BMG在人工唾液中的极化阻值均大于316L SS。铁基BMG的点蚀电位远高于316L不锈钢，导致离子释放到电解液中很少，而316L不锈钢在相同条件下有大量的Ni和Fe离子释放。间接细胞毒性实验结果表明，三种铁基BMG提取物对L929和NIH3T3细胞均无细胞毒作用。这些结果表明，铁基BMG材料将为生物医学，特别是在牙科种植学中的应用开辟一条新的途径。
The aim of this work is to investigate the corrosion resistance and biocompatibility of three kinds of Fe based bulk metallic glasses (BMGs), Fe41Co7Cr15Mo14C15B6Y2(BMG1), (Fe44Cr5Co5Mo13Mn11C16B6)98Y2(BMG2), and Fe48Cr15Mo14C15B6Er2(BMG3) by electrochemical measurements and indirect contact cytotoxicity assays, respectively. In comparison with 316L SS biomedical steel, Fe based BMGs show better corrosion resistance in both simulated body fluids (Hank's solution and artificial saliva). The OCP curves show that the passive film on the Fe based BMG surfaces is quite stable, like 316L SS. The corrosion current densities obtained from the anodic polarization curves from the lowest to highest are as follows: BMG3<BMG1<BMG2<316L SS. The EIS analysis indicates that the Fe Based BMGs have larger polarization resistance value than that of 316L SS except for BMG2 in artificial saliva. The pitting corrosion potentials of Fe based BMGs are much higher than that of the 316L SS, resulting in very few ions releasing into the electrolytes while a significant amount of Ni and Fe ions release was found for 316L SS under the same condition. The indirect cytotoxicity results suggest that all three Fe based BMG extracts have no cytotoxicity to L929 and NIH3T3 cells. All these results demonstrate that Fe based BMGs will open up a new path for the biomedical applications, especially in dental implantology.
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影响因子：
8.3
作者：
S. Hiromoto;A. Tsai;M. Sumita;T. Hanawa
通讯作者：
S. Hiromoto;A. Tsai;M. Sumita;T. Hanawa
影响因子：
14
作者：
Fleury, C;Petit, A;Huk, OL
通讯作者：
Huk, OL
DOI：
10.1016/j.msea.2007.01.044
发表时间：
2007-06
影响因子：
6.4
作者：
Shengli Zhu;Xin-min Wang;F. Qin;A. Inoue
通讯作者：
Shengli Zhu;Xin-min Wang;F. Qin;A. Inoue
DOI：
10.1002/jbm.a.30502
发表时间：
2005-12
期刊：
Journal of biomedical materials research. Part A
影响因子：
--
作者：
C. Qiu;L. Liu;M. Sun;S. Zhang
通讯作者：
C. Qiu;L. Liu;M. Sun;S. Zhang
DOI：
10.1002/jbm.b.30206
发表时间：
2005-05
期刊：
Journal of biomedical materials research. Part B, Applied biomaterials
影响因子：
--
作者：
Hyung-Min Shim;K. Oh;Jae-Young Woo;C. Hwang;Kyoung-Nam Kim
通讯作者：
Hyung-Min Shim;K. Oh;Jae-Young Woo;C. Hwang;Kyoung-Nam Kim