Metabolic compensation and circadian resilience in prokaryotic cyanobacteria.
Metabolic compensation and circadian resilience in prokaryotic cyanobacteria.
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DOI：
10.1146/annurev-biochem-060713-035632
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发表时间：
2014
影响因子：
16.6
通讯作者：
Egli M
中科院分区：
文献类型：
--
作者：
Johnson CH;Egli M
For a biological oscillator to function as a circadian pacemaker that confers a fitness advantage, its timing functions must be stable in response to environmental and metabolic fluctuations. One such stability enhancer, temperature compensation, has long been a defining characteristic of these timekeepers. However, an accurate biological timekeeper must also resist changes in metabolism, and this review suggests that temperature compensation is actually a subset of a larger phenomenon, namely metabolic compensation, which maintains the frequency of circadian oscillators in response to a host of factors that impinge on metabolism and would otherwise destabilize these clocks. The circadian system of prokaryotic cyanobacteria is an illustrative model because it is composed of transcriptional and nontranscriptional oscillators that are coupled to promote resilience. Moreover, the cyanobacterial circadian program regulates gene activity and metabolic pathways, and it can be manipulated to improve the expression of bioproducts that have practical value.
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影响因子：
9.9
作者：
Clodong, Sebastien;Duhring, Ulf;Kronk, Luiza;Wilde, Annegret;Axmann, Ilka;Herzel, Hanspeter;Kollmann, Markus
通讯作者：
Kollmann, Markus
影响因子：
5.7
作者：
Egli M;Johnson CH
通讯作者：
Johnson CH
影响因子：
9.9
作者：
Brettschneider, Christian;Rose, Rebecca J.;Hertel, Stefanie;Axmann, Ilka M.;Heck, Albert J. R.;Kollmann, Markus
通讯作者：
Kollmann, Markus
DOI：
10.1073/pnas.1118726109
发表时间：
2012-04-03
影响因子：
11.1
作者：
Eckel-Mahan, Kristin L.;Patel, Vishal R.;Sassone-Corsi, Paolo
通讯作者：
Sassone-Corsi, Paolo
影响因子：
10.5
作者：
Cheng, P;He, Q;Liu, Y
通讯作者：
Liu, Y