Diagnosis of human sleeping sickness: sense and sensitivity.
Diagnosis of human sleeping sickness: sense and sensitivity.
复制标题
人类昏睡病的诊断：感觉和敏感性。
DOI：
10.1016/j.pt.2011.04.005
复制
发表时间：
2011
影响因子：
9.6
通讯作者：
S. Welburn
中科院分区：
文献类型：
--
作者：
Sally L. Wastling;S. Welburn
In 1997 the World Health Organization (WHO) advocated increased access to diagnosis and treatment, as well as reinforcement of surveillance, for the control of sleeping sickness (human African trypanosomiasis, HAT). This coincided with the end of decades of civil conflicts in several endemic regions and negotiation of a sustainable supply of ‘free' curative drugs and, as a result, HAT is at its lowest level in 50 years. However, reported cases underestimate prevalence and downplay HAT when compared with data generated by advanced diagnostic capacity for human immunodeficiency virus (HIV), tuberculosis (TB) and malaria, and, because HAT case numbers fall between epidemics, diagnostics become less commercially appealing. Here recent trends in the development of diagnostics for sleeping sickness are considered and progress towards a much-needed sensitive, specific and affordable point-of-care diagnostic is assessed.
DOI：
10.1073/pnas.87.5.1874
发表时间：
1990-03-01
影响因子：
11.1
作者：
GUATELLI, JC;WHITFIELD, KM;GINGERAS, TR
通讯作者：
GINGERAS, TR
DOI：
10.1073/pnas.92.10.4641
发表时间：
1995-05-09
影响因子：
11.1
作者：
FIRE, A;XU, SQ
通讯作者：
XU, SQ