Biomimetic Dextran Coatings On Silicon Wafers: Thin Film Properties And Wetting
Biomimetic Dextran Coatings On Silicon Wafers: Thin Film Properties And Wetting
复制标题
硅片上的仿生葡聚糖涂层：薄膜特性和润湿
DOI：
10.1557/proc-734-b10.7
复制
发表时间：
2002
期刊：
影响因子：
--
通讯作者：
R. Composto
中科院分区：
文献类型：
--
作者：
M. Ombelli;D. Eckmann;R. Composto
最近人们对用于生物技术应用的多糖涂层产生了很大的兴趣。我们通过两步工艺获得了应用于平坦硅片表面的高度可润湿的葡聚糖涂层：第一步，通过沉积 3-氨基丙基三乙氧基硅烷 (APTES) 自组装单层对硅进行胺化；第二步，将分子量范围为1 kDa至100 kDa的多分散性和低分散性葡聚糖沿着主链共价接枝到表面氨基上，以实现强界面锚定。研究了葡聚糖浓度对膜厚度和接触角的影响。原子力显微镜 (AFM) 已用于表征表面粗糙度和葡聚糖以及 APTES 单层的覆盖度。还测试了合成表面的气泡粘附性能。
There has been much recent interest in polysaccharide coatings for biotechnology applications. We obtained highly wettable dextran coatings applied to flat silicon wafer surfaces through a two-step process: in the first step, the silicon is aminated by the deposition of a self-assembled monolayer of 3-aminopropyltriethoxysilane (APTES); in the second step, polydisperse and low dispersity dextrans with molecular weights ranging from 1 kDa to 100 kDa are covalently grafted along the backbone to the surface amino groups to achieve strong interfacial anchoring. The effect of dextran concentration on film thickness and contact angle is investigated. Atomic force microscopy (AFM) has been employed to characterize surface roughness and coverage of the dextrans as well as the APTES monolayers. The synthetic surfaces were also tested for gas bubble adhesion properties.
影响因子：
14
作者：
Massia, SP;Stark, J;Letbetter, DS
通讯作者：
Letbetter, DS