Variability of quadriceps femoris motor neuron discharge and muscle force in human aging.
Variability of quadriceps femoris motor neuron discharge and muscle force in human aging.
复制标题
人类衰老过程中股四头肌运动神经元放电和肌力的变异性。
DOI：
10.1007/s00221-006-0785-z
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发表时间：
2007
影响因子：
2
通讯作者：
Tracy,BrianL
中科院分区：
文献类型：
--
作者：
Welsh,SethJ;Dinenno,DevinV;Tracy,BrianL
目的是确定视觉反馈的贡献和老化对膝伸肌（KE）肌力和运动单位（MU）放电的变异性的影响。在两种类型的等长试验期间记录单个MU，（1）在试验期间提供视觉反馈（维斯），然后移除（NO维斯）（34个MU来自年轻人，32个来自老年人），以及（2）在试验期间仅NO维斯（66个MU来自年轻人，77个来自老年人）。招募阈值（RT）范围为0 - 37% MVC。标准差（SD）和变异系数（CV）的肌肉力量和MU峰间期（ISI）的测量在稳定的收缩在目标力范围从0.3%至54%MVC。在分析之前去除力漂移（<0.5Hz）。维斯/NO维斯试验：老年MU从维斯到NO维斯的ISI的CV下降（12.5 ± 4.1到9.94 ± 2.6%）大于年轻MU（10.6 ± 3.3到10.3 ± 2.8%，年龄组×视力相互作用，P = 0.006）。老年人从维斯到NO维斯的力的CV变化（1.45 - 1.05%）显著大于年轻人（1.42 - 1.41%）。仅NOVIS试验：对于所有MU，平均RT（6.6 ± 7.7% MVC），目标力高于RT（1.20 ± 2.7% MVC），ISI的SD（0.012 ± 0.005 s），和ISI的简历（11.1 ± 3.3%）相似。在0 - 3%MVC之间的试验中，各年龄组的力CV相似（1.74 ± 0.74%），年轻受试者在3 - 10%MVC（1.47 ± 0.5 vs. 1.21 ± 0.4%）和> 10%MVC（1.44 ± 0.6 vs. 1.01 ± 0.3%）时更大。在RT的0 - 3%、3 - 10%和> 10%的区间内，MU的ISI的CV在年龄组之间相似。因此，视力矫正对运动单位放电和力的变异性的贡献对于老年人更大。视觉反馈的存在似乎是必要的，以找到更大的放电变异性运动单位从膝伸肌的老年人。
The purpose was to determine the contribution of visual feedback and the effect of aging on the variability of knee extensor (KE) muscle force and motor unit (MU) discharge. Single MUs were recorded during two types of isometric trials, (1) visual feedback provided (VIS) and then removed (NOVIS) during the trial (34 MUs from young, 32 from elderly), and (2) only NOVIS (66 MUs from young, 77 from elderly) during the trial. Recruitment threshold (RT) ranged from 0–37% MVC. Standard deviation (SD) and coefficient of variation (CV) of muscle force and MU interspike interval (ISI) was measured during steady contractions at target forces ranging from 0.3 to 54% MVC. Force drift (<0.5 Hz) was removed before analysis. VIS/NOVIS trials: the decrease in the CV of ISI from VIS to NOVIS was greater for MUs from elderly (12.5 ± 4.1 to 9.94 ± 2.6%) than young (10.6 ± 3.3 to 10.3 ± 2.8%, age group × vision interaction,P= 0.006). The change in CV of force from VIS to NOVIS was significantly greater for elderly (1.45 to 1.05%) than young (1.42 to 1.41%). NOVIS only trials: for all MUs, the average RT (6.6 ± 7.7 % MVC), target force above RT (1.20 ± 2.7% MVC), SD of ISI (0.012 ± 0.005 s), and CV of ISI (11.1 ± 3.3%) were similar for young and elderly MUs. The CV of force was similar between age groups for trials between 0 and 3% MVC (1.74 ± 0.74%) and was greater for young subjects from 3 to 10% MVC (1.47 ± 0.5 vs. 1.21 ± 0.4%) and >10% MVC (1.44 ± 0.6 vs. 1.01 ± 0.3%). The CV of ISI was similar between age groups for MUs in 0–3, 3–10, and >10% bins of RT. Thus, the contribution of visuomotor correction to the variability of motor unit discharge and force is greater for elderly adults. The presence of visual feedback appears to be necessary to find greater discharge variability in motor units from the knee extensors of elderly adults.
[体外冲击波对痉挛性运动障碍儿童肌肉功能障碍影响的初步研究]。
影响因子：
1
作者：
H. Lohse;M. Kraemer;U. Reime
通讯作者：
U. Reime
影响因子：
5.1
作者：
Holfeld, Johannes;Tepekoeylue, Can;Paulus, Patrick
通讯作者：
Paulus, Patrick
影响因子：
37.8
作者：
Aicher, Alexandra;Heeschen, Christopher;Dimmeler, Stefanie
通讯作者：
Dimmeler, Stefanie