Longitudinal study of untreated periodontitis (II). Microbiological findings.

Longitudinal study of untreated periodontitis (II). Microbiological findings.
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未经治疗的牙周炎的纵向研究(II)。

DOI:
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发表时间:
1988
影响因子:
6.7
通讯作者:
D. McKenzie
D. McKenzie
中科院分区:
医学1区
文献类型:
--
作者:
T. Macfarlane;W.M.M. Jenkins;W. Gilmour;J. McCourtie;D. McKenzie

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11名患有晚期慢性牙周炎的志愿者参加了一项为期1年的纵向临床和微生物研究。在左颌象限148个预先选择的地点(测试地点)的7次访问中,每次都收集牙龈下菌斑,在第一次和最后一次访问中,仅从左颌象限的117个地点(对照地点)收集菌斑。在7次访问中,每次对所有部位进行临床检查,调查的微生物标志物为龈下菌斑中%螺旋体和%黑色色素拟杆菌。研究结束后,对各位点探测依恋水平的顺序变化进行回归分析,确定依恋变化的方向和程度。利用个体位点和个体受试者,研究了附着变化与%螺旋体或%黑色色素拟杆菌之间可能的相关性。在试验点和对照点之间,没有观察到任何微生物变量的显著差异。在基线、12个月就诊时以及使用所有7次就诊中积累的微生物数据调查微生物标志物与依恋变化之间可能的相关性。只有在12个月的访问中观察到显著差异,在依恋水平改善最大的受试者中,试验点和对照点的螺旋体百分比均显著降低。总的来说,这些结果表明,无论是螺旋体还是黑色拟杆菌种类的定量都不能可靠地用于识别或预测疾病活性部位。
11 volunteer subjects with advanced chronic periodontitis participated in a 1-year longitudinal clinical and microbiological study. Subgingival plaque was collected at each of 7 visits from 148 pre-selected sites in the left jaw quadrants (test sites) and on the first and last visits, only from 117 sites in the left jaw quadrants (control sites). All sites were examined clinically at each of the 7 visits, and the microbiological markers investigated were the % spirochaetes and % black pigmented Bacteroides species in subgingival plaque. At the completion of the study, the sequential changes in probing attachment level at each site were subjected to regression analysis to determine the direction and extent of attachment change. Possible correlations between attachment change and % spirochaetes or % black-pigmented bacteroides were investigated using both individual sites and individual subjects. No significant differences were observed in either of the microbial variables between test and control sites. Possible correlations between the microbiological markers and attachment changes were investigated at baseline, at the 12-month visit and using the microbial data accumulated over all 7 visits. Significant differences were observed only at the 12-month visit when the % spirochaetes of both test and control sites were significantly lower in subjects showing the greatest improvement in attachment level. Overall, these results indicate that quantification of either spirochaetes or black-pigmented Bacteroides species cannot be used reliably to identify or predict disease-active sites.
DOI: 10.1111/j.1600-051x.1985.tb01388.x
发表时间: 1985
影响因子: 6.7
作者:
Slots,J;Emrich,LJ;Genco,RJ;Rosling,BG
通讯作者: Rosling,BG
DOI: 10.1111/j.1600-051x.1986.tb00867.x
发表时间: 1986
影响因子: 6.7
作者:
Listgarten,MA;Levin,S;Schifter,CC;Sullivan,P;Evian,CI;Rosenberg,ES;Laster,L
通讯作者: Laster,L
对牙齿表面的龈下细菌进行比较差示暗视野显微镜检查,并有复发性牙周炎的最新证据和未受影响的表面。
DOI: 10.1902/jop.1984.55.7.398
发表时间: 1984
影响因子: 4.3
作者:
Listgarten,MA;Levin,S;Schifter,CC;Sullivan,P;Evian,CI;Rosenberg,ES
通讯作者: Rosenberg,ES
DOI: 10.1902/jop.1981.52.8.435
发表时间: 1981
影响因子: 4.3
作者:
Rosenberg,ES;Evian,CI;Listgarten,MA
通讯作者: Listgarten,MA