Malignant pancreatic serous cystic neoplasms: systematic review with a new case
Malignant pancreatic serous cystic neoplasms: systematic review with a new case
复制标题
胰腺恶性浆液性囊性肿瘤：新病例的系统评价
作者：
Jimi Huh;J. Byun;Seung‐Mo Hong;K. Kim;J. Kim;S. S. Lee;Hyoung;Moon‐gyu Lee
BackgroundThis study analyses the clinical pancreas serous cystic neoplasm（SCN）of the pancreas through systematic review and a institutional case report.MethodsA comprehensive literature search was performed in the MEDLINE database to identify studies on malignant SCNs of the pancreas that had detailed clinical pancreas and radiologic information.还对我们的机构数据库进行了计算机系统检索，以确定恶性SCN病例，以补充系统评价。使用最终纳入的情况下，我们分析了恶性SCNs的临床病理和放射学特征的pancreat.ResultsA审查136候选文章确定了26项研究，26例有详细的临床信息。我们的机构数据搜索增加了一个案例。对27例病例的系统回顾显示，原发性肿瘤（平均直径10.2 ± 4.0 cm）主要累及胰腺体尾（n = 16），常侵犯邻近器官（n = 19）。14例患者发生远处转移（同步性，n = 5;异时性，n = 8;两者，n = 1），最常见于肝脏（n = 13）。胰腺恶性SCNs的影像学特征与良性SCNs相同，除了局部浸润或远处转移。预后是优秀的，17人活着的写作时，中位随访期为2 years.ConclusionsThe恶性潜力的SCNs的胰腺应考虑在胰腺SCNs患者的诊断和管理。
BackgroundThis study analyzes the clinicopathologic and radiologic characteristics of malignant serous cystic neoplasm (SCN) of the pancreas through systematic review and an institutional case report.MethodsA comprehensive literature search was performed in the MEDLINE database to identify studies on malignant SCNs of the pancreas that had detailed clinicopathologic and radiologic information. A computerized systematic search of our institutional database was also performed to identify cases of malignant SCN for addition to the systematic review. Using the final included cases, we analyzed the clinicopathologic and radiologic features of malignant SCNs of the pancreas.ResultsA review of 136 candidate articles identified 26 studies with 26 cases that had detailed clinical information. Our institutional data search added one case. The systematic review of the 27 cases revealed that primary tumors (mean diameter 10.2 ± 4.0 cm) mainly involved the body and tail of the pancreas (n = 16) and frequently invaded adjacent organs (n = 19). Distant metastases occurred in 14 patients (synchronous, n = 5; metachronous, n = 8; both, n = 1), most commonly in the liver (n = 13). Imaging features of malignant SCNs of the pancreas were identical to the benign counterpart, except local invasion or distant metastases. The prognosis was excellent in that 17 were alive at the time of writing with a median follow-up period of 2 years.ConclusionsThe malignant potential of SCNs of the pancreas should be considered in the diagnosis and management of patients with pancreatic SCNs.
影响因子：
3.8
作者：
Valsangkar, Nakul P.;Morales-Oyarvide, Vicente;Thayer, Sarah P.;Ferrone, Cristina R.;Wargo, Jennifer A.;Warshaw, Andrew L.;Fernandez-del Castillo, Carlos
通讯作者：
Fernandez-del Castillo, Carlos