Self-stimulation in 7- and 10-day-old rats.
Self-stimulation in 7- and 10-day-old rats.
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7 日龄和 10 日龄大鼠的自我刺激。
DOI：
10.1037//0735-7044.98.3.479
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发表时间：
1984
影响因子：
1.9
通讯作者：
G. Barr
中科院分区：
文献类型：
--
作者：
T. Lithgow;G. Barr
最近，有研究表明，幼鼠表现出成年鼠特有的习得行为。使用改进的自我刺激范式，这项研究探索了7日龄和10日龄的大鼠幼鼠是否能够学习辨别的操作符，以在支持成年大鼠自我刺激的神经部位获得直接电刺激。通过轻推两个反应机械手中的一个，在两个年龄(7天和10天)和温度(22和35摄氏度)下，在不同的前脑部位植入电极进行自我刺激，包括前额叶皮质、终纹床核、杏仁内侧核和前脑束内侧。唯一对温度敏感的部位可能是伏隔核，只有在10日龄温度较高时才呈阳性。这些结果表明，在断奶前的大鼠幼鼠中，几个前脑部位表现出有益的刺激特性。
Recently, it has been shown that the infant rat exhibits learned behaviors characteristic of the adult. With a modified self-stimulation paradigm, this study explored whether 7- and 10-day-old rat pups could learn a discriminated operant to obtain direct electrical stimulation in neural sites that support self-stimulation in adults. By nudging one of two response manipulanda, at two ages (7 and 10 days) and temperatures (22 and 35 degrees C), pups self-stimulated with electrodes implanted in a variety of forebrain sites, including the prefrontal cortex, bed nucleus of the stria terminalis, medial nucleus of the amygdala, and the medial forebrain bundle. The only temperature-sensitive site might be the nucleus accumbens which was positive only at the higher temperature in 10-day-olds. These results indicate that several forebrain sites demonstrate rewarding properties of stimulation in the preweanling rat pup.
3天大的幼鼠颅内自我刺激。
DOI：
10.1126/science.6975999
发表时间：
1981
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Moran,TH;Lew,MF;Blass,EM
通讯作者：
Blass,EM