Inhaled toluene produces pentobarbital-like discriminative stimulus effects in mice.
Inhaled toluene produces pentobarbital-like discriminative stimulus effects in mice.
复制标题
吸入甲苯对小鼠产生类似戊巴比妥的辨别刺激作用。
DOI:
10.1016/0024-3205(85)90247-4
复制
发表时间:
1985
期刊:
影响因子:
6.1
通讯作者:
Balster,RL
中科院分区:
文献类型:
--
作者:
Rees,DC;Coggeshall,E;Balster,RL
The abuse of volatile solvents may be due to their ability to produce an intoxication similar to that produced by classical central nervous system depressants such as the barbiturates and ethanol. To evaluate this hypothesis, mice were trained to discriminate pentobarbital from saline injections in a two-lever operant task. Stimulus generalization was examined following 20-min inhalation exposures to toluene (300–5400 ppm). In 8 of 10 subjects, pentobarbital-lever responding occurred following toluene exposure indicating an overlap in the discriminative stimulus properties of toluene and pentobarbital.
登录
查看更多内容
DOI:
--
发表时间:
1978
期刊:
影响因子:
--
作者:
T. L. Cook;M. Smith;P. Winter;J. Starkweather;E. Eger
通讯作者:
E. Eger
影响因子:
3.8
作者:
M. E. Goldberg;C. Haun;H. F. Smyth
通讯作者:
H. F. Smyth
影响因子:
5.7
作者:
B. Wolfson;B. Freed
通讯作者:
B. Freed
影响因子:
3.8
作者:
Ronald W. Wood;David C. Rees;V. Laties
通讯作者:
V. Laties
影响因子:
5.6
作者:
A. Raines;G. J. Blake;Bernice Richardson;Mark B. Gilbert
通讯作者:
Mark B. Gilbert