Evaluation of a rapid, multiphase MRE sequence in a heart-simulating phantom.
Evaluation of a rapid, multiphase MRE sequence in a heart-simulating phantom.
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DOI：
10.1002/mrm.22048
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发表时间：
2009-09
影响因子：
3.3
通讯作者：
Ehman, Richard L.
中科院分区：
文献类型：
--
作者：
Kolipaka, Arunark;McGee, Kiaran P.;Araoz, Philip A.;Glaser, Kevin J.;Manduca, Armando;Ehman, Richard L.
本研究的目的是通过与使用单相磁共振弹性成像（MRE）序列获得的刚度估计值进行比较，验证使用多相磁共振弹性成像（MRE）成像序列获得的循环变形体模的刚度估计值，并量化作为变形频率和成像参数函数的多相衍生刚度估计值的稳定性。将直径为10 cm、厚度为1 cm的球形橡胶壳连接至计算机化的流量泵，以在体模内产生循环压力变化。使用单相和多相MRE采集，在18-72 bpm之间的循环压力下对体模进行成像。使用球壳波反演算法解决了体模的剪切刚度。剪切刚度在感兴趣的切片上取平均值，并针对体模内的压力作图。刚度和压力之间观察到线性相关性。使用标准单相和多相脉冲序列获得的刚度估计值之间观察到良好的相关性（R2=0.98）。当采集单个图像所需的变形期分数不大于42%时，使用多相MRE获得的刚度估计值是稳定的。结果表明，多相磁共振成像技术的潜力，为动态器官，如心脏。
The aims of this study were to validate stiffness estimates of a phantom undergoing cyclic deformation obtained using a multi-phase magnetic resonance elastography (MRE) imaging sequence by comparison with those obtained using a single-phase MRE sequence and to quantify the stability of the multi-phase-derived stiffness estimates as a function of deformation frequency and imaging parameters. A spherical rubber-shell of 10 cm diameter and 1 cm thickness was connected to a computerized flow pump to produce cyclic pressure variations within the phantom. The phantom was imaged at cyclic pressures between 18–72 bpm using single-phase and multi-phase MRE acquisitions. The shear stiffness of the phantom was resolved using a spherical-shell wave inversion algorithm. Shear stiffness was averaged over the slice of interest and plotted against pressure within the phantom. A linear correlation was observed between stiffness and pressure. Good correlation (R2=0.98) was observed between the stiffness estimates obtained using the standard single-phase and the multi-phase pulse sequences. Stiffness estimates obtained using multi-phase MRE were stable when the fraction of the deformation period required for acquisition of a single image was not greater than 42%. The results demonstrate the potential of multi-phase MRE technique for imaging dynamic organs, such as the heart.
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DOI：
10.1111/j.1540-8175.1998.tb00629.x
发表时间：
1998-07-01
影响因子：
1.5
作者：
Domanski, MJ;Follman, D;Mirsky, I
通讯作者：
Mirsky, I
影响因子：
12.6
作者：
Yin, Meng;Talwalkar, Jayant A.;Ehman, Richard L.
通讯作者：
Ehman, Richard L.
影响因子：
2.9
作者：
Sack, Ingolf;Beierbach, Bernd;Braun, Juergen
通讯作者：
Braun, Juergen
影响因子：
56.9
作者：
MUTHUPILLAI, R;LOMAS, DJ;EHMAN, RL
通讯作者：
EHMAN, RL
影响因子：
2.5
作者：
Inoue, Y;Nomura, Y;Ohtomo, K
通讯作者：
Ohtomo, K