Cyclopiazonic acid biosynthesis of Aspergillus flavus and Aspergillus oryzae.
Cyclopiazonic acid biosynthesis of Aspergillus flavus and Aspergillus oryzae.
复制标题
作者：
Chang PK;Ehrlich KC;Fujii I
环匹阿尼酸 (CPA) 是一种吲哚四甲酸神经毒素，由产生黄曲霉毒素的黄曲霉某些菌株和某些米曲霉菌株产生。尽管它在 40 年前就被发现了，但对其毒性和生物合成的评论却很少报道。本综述探讨了目前已知的 CPA 本身或与其他霉菌毒素组合对动物和人类的毒性。该综述还讨论了黄曲霉/米曲霉种群中 CPA 的生物合成和 CPA 生产的遗传多样性。
Cyclopiazonic acid (CPA) is an indole-tetramic acid neurotoxin produced by some of the same strains of A. flavus that produce aflatoxins and by some Aspergillus oryzae strains. Despite its discovery 40 years ago, few reviews of its toxicity and biosynthesis have been reported. This review examines what is currently known about the toxicity of CPA to animals and humans, both by itself or in combination with other mycotoxins. The review also discusses CPA biosynthesis and the genetic diversity of CPA production in A. flavus/oryzae populations.
登录
查看更多内容
影响因子：
5.4
作者：
Antony, M;Shukla, Y;Janardhanan, KK
通讯作者：
Janardhanan, KK
DOI：
10.1016/j.ijfoodmicro.2005.11.008
发表时间：
2006-04-25
影响因子：
5.4
作者：
Chang, PK;Ehrlich, KC;Hua, SST
通讯作者：
Hua, SST
影响因子：
2.9
作者：
Andreassi, John L., II;Vetting, Matthew W.;Bilder, Patrick W.;Roderick, Steven L.;Leyh, Thomas S.
通讯作者：
Leyh, Thomas S.
影响因子：
2.9
作者：
Edmondson, Dale E.;Binda, Claudia;Wang, Jin;Upadhyay, Anup K.;Mattevi, Andrea
通讯作者：
Mattevi, Andrea
影响因子：
3.2
作者：
COTTY, PJ
通讯作者：
COTTY, PJ