Precise definition of anonymization in genetic polymorphism studies.
Precise definition of anonymization in genetic polymorphism studies.
复制标题
遗传多态性研究中匿名化的精确定义。
DOI：
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复制
发表时间：
2004
影响因子：
--
通讯作者：
A. Tamakoshi
中科院分区：
文献类型：
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作者：
N. Hamajima;Y. Atsuta;Y. Niwa;K. Nishio;Daisuke Tanaka;Kazuhito Yamamoto;A. Tamakoshi
匿名化是流行病学研究中保护受试者隐私的重要工具。本文对遗传多态性研究中的匿名化类型进行了分类，提供了精确的定义。它们是：1）在没有参与者列表的情况下在登记时的非匿名化; 2）在使用参与者列表进行基因分型之前的非匿名化; 3）匿名化; 4）针对外部人员的非匿名化;以及5）针对外部人员的匿名化。考虑到包括基因型数据和可直接识别数据（如姓名）的表格的可访问性，分类是重要的;如果存在此类表格，工作人员可以获得有关参与者的基因型信息。前三种模式在这里被定义为研究人员无法访问具有直接可识别信息的基因型数据的匿名化。通过上述任何匿名化模式，参与者可以通过电话或互联网访问自己的基因型，参与者可以通过参与者持有的关键代码进行匿名化。2001年3月29日，日本三个省合作发布了一项指南，其中定义了“匿名化”和“非匿名化”，“目的是防止个人信息违反法律、本指南或研究协议向外泄露”，但实际上内容并不明确。建议的定义将是有用的，当我们描述和讨论一个给定的多态性研究的匿名化的首选模式。
Anonymization is an essential tool to protect privacy of participants in epidemiological studies. This paper classifies types of anonymization in genetic polymorphism studies, providing precise definitions. They are: 1) unlinkable anonymization at enrollment without a participant list; 2) unlinkable anonymization before genotyping with a participant list; 3) linkable anonymization; 4) unlinkable anonymization for outsiders; and 5) linkable anonymization for outsiders. The classification in view of accessibility to a table including genotype data with directly identifiable data such as names is important; if such tables exist, staff may obtain genotype information about participants. The first three modes are defined here as anonymization unaccessible to genotype data with directly identifiable information for research staff. Anonymization with a key code held by participants is possible with any of the above anonymization modes, by which participants can access to their own genotypes through telephone or internet. A guideline issued on March 29, 2001 with collaboration of three Ministries in Japan defines "anonymization in a linkable fashion" and "anonymization in an unlinkable fashion", "for the purpose of preventing the personal information from being divulged externally in violation of law, the present guidelines or a research protocol", but the contents are not clear in practice. The proposed definitions will be useful when we describe and discuss the preferable mode of anonymization for a given polymorphism study.
将遗传易感性反馈纳入针对低收入非裔美国吸烟者的戒烟计划中。
DOI：
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发表时间：
2002
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
影响因子：
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作者：
McBride,ColleenM;Bepler,Gerold;Lipkus,IsaacM;Lyna,Pauline;Samsa,Greg;Albright,Jennifer;Datta,Santanu;Rimer,BarbaraK
通讯作者：
Rimer,BarbaraK
癌症控制研究2001。
DOI：
10.1023/a:1008953206396
发表时间：
2000
期刊：
Cancer causes & control : CCC
影响因子：
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作者：
Rimer,BK
通讯作者：
Rimer,BK