Respiratory outcomes after initial hospital discharge in children with ventricular shunts and bronchopulmonary dysplasia.
Respiratory outcomes after initial hospital discharge in children with ventricular shunts and bronchopulmonary dysplasia.
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DOI：
10.1002/ppul.23792
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发表时间：
2017-10
影响因子：
3.1
通讯作者：
Collaco JM
中科院分区：
文献类型：
--
作者：
McGrath-Morrow SA;Ahn ES;Collaco JM
早产儿因出血后脑积水而需要放置脑室分流管，其神经发育迟缓的风险增加。我们假设患有支气管肺发育不良（BPD）的早产儿需要放置脑室分流（VS），由于其神经发育延迟的可能性较高，因此其长期呼吸道疾病的风险增加。我们还假设患有BPD和脑室分流的儿童在初次分流放置后的早期儿童期需要频繁的分流翻修。所有受试者均于2008年1月至2016年11月期间从约翰霍普金斯支气管肺发育不良诊所招募。对人口统计学和临床信息进行了审查，并由主要照顾者完成了呼吸结局问卷。研究人群的623例受试者中有55例（8.9%）存在心室分流，平均随访数据为4.6 ± 2.3年（范围：0.5 - 10.1）。与单独的BPD受试者相比，患有VS的受试者更有可能在较早的胎龄出生，并在补充氧气的情况下出院。两组的门诊呼吸道症状和急性护理使用情况相似。VS的BPD受试者更有可能放置胃管。在VS受试者中共进行了270例神经外科手术，平均为4.9 ± 5.4例手术/受试者。与单独BPD儿童相比，心室分流和BPD儿童的门诊呼吸结局相似;然而，VS + BPD组中更多使用胃管可能减轻了呼吸道发病率。多个神经外科手术是常见的儿童脑室分流。
Children born premature who require ventricular shunt placement for post hemorrhagic hydrocephalus are at increased risk for neurodevelopmental delay. We hypothesized that preterm infants with bronchopulmonary dysplasia (BPD) who require ventricular shunt (VS) placement are at additive risk for long-term respiratory morbidities due to their higher likelihood of neurodevelopmental delay. We also hypothesized that children with BPD and ventricular shunts would require frequent shunt revisions during early childhood following initial shunt placement. All subjects were recruited from the Johns Hopkins Bronchopulmonary Dysplasia Clinic between January 2008 and November 2016. A review of demographic and clinical information was undertaken and a respiratory outcomes questionnaire was completed by the primary caregiver. Fifty-five (8.9%) of 623 subjects in the study population had ventricular shunts, with a mean 4.6 ± 2.3 years of follow-up data (range: 0.5–10.1). Subjects with VS were more likely to be born at earlier gestational ages and be discharged on supplemental oxygen compared to BPD subjects alone. Outpatient respiratory symptoms and acute care usage were similar between the two groups. BPD subjects with VS were more likely to have had gastric tubes placed. A total of 270 neurosurgical procedures were performed in subjects with VS with a mean of 4.9 ± 5.4 procedures/subject. Children with ventricular shunts and BPD had similar outpatient respiratory outcomes compared to children with BPD alone; however respiratory morbidities may have been mitigated by the greater use of gastric tubes in the VS + BPD group. Multiple neurosurgical procedures were common in children with ventricular shunts.
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影响因子：
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作者：
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DOI：
10.1164/rccm.201101-0055oc
发表时间：
2011-06-15
影响因子：
24.7
作者：
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