Selection, characterisation and mapping of complex electrochemical processes at individual single-walled carbon nanotubes: the case of serotonin oxidation.
Selection, characterisation and mapping of complex electrochemical processes at individual single-walled carbon nanotubes: the case of serotonin oxidation.
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单个单壁碳纳米管复杂电化学过程的选择、表征和绘图：血清素氧化的情况。
DOI：
10.1039/c4fd00054d
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发表时间：
2014
影响因子：
3.4
通讯作者：
Güell AG
中科院分区：
文献类型：
--
作者：
Güell AG
利用一种新型平台，以高分辨率研究了神经递质5 -羟色胺在单个单壁碳纳米管（SWNTs）上的电化学（EC）氧化，该平台将流取向碳纳米管与原子力显微镜、拉曼显微镜、电子电导测量、单个SWNT电化学和高分辨率扫描电化学细胞显微镜（SECCM）相结合。SECCM已用于可视化沿金属swcnts侧壁部分的EC活性，以评估侧壁在多大程度上促进了这一复杂的多步骤过程的电化学。观察到均匀且高的EC活性，这与侧壁的显著反应一致，而不是仅由缺陷驱动的电化学。通过对SWNT同一区域的正向和反向扫描（追踪和回溯），也可以评估血清素氧化反应产物对EC活性的任何阻断。在生理相关浓度（5 μM）下，没有检测到单壁碳纳米管阻滞，这可以归因于（至少部分归因于）SECCM格式中单个分离的单壁碳纳米管的高扩散速率。在较高的5 -羟色胺浓度（2毫米）下，氧化产物形成的低聚物更为显著，从SECCM半月板在SWNT上移动时记录的线条曲线可以观察到EC过程的主要阻断。SECCM线轮廓形态显示出在EC过程中是否发生阻塞的高度诊断。本文的研究增加了越来越多的证据表明，从简单的外球氧化还原反应到复杂的多步骤过程，各种碳纳米管的EC过程在原始碳纳米管上很容易发生。所描述的平台普遍适用于各种类型的纳米结构和纳米线。
The electrochemical (EC) oxidation of the neurotransmitter, serotonin, at individual single-walled carbon nanotubes (SWNTs) is investigated at high resolution using a novel platform that combines flow-aligned SWNTs with atomic force microscopy, Raman microscopy, electronic conductance measurements, individual SWNT electrochemistry and high-resolution scanning electrochemical cell microscopy (SECCM). SECCM has been used to visualise the EC activity along side-wall sections of metallic SWNTs to assess the extent to which side-walls promote the electrochemistry of this complex multi-step process. Uniform and high EC activity is observed that is consistent with significant reaction at the side-wall, rather than electrochemistry being driven by defects alone. By scanning forward and reverse (trace and retrace) over the same region of a SWNT, it is also possible to assess any blocking of EC activity by serotonin oxidation reaction products. At a physiologically relevant concentration (5 μM), there is no detectable blocking of SWNTs, which can be attributed, at least in part, to the high diffusion rate to an individual, isolated SWNT in the SECCM format. At higher serotonin concentration (2 mM), oligomer formation from oxidation products is much more significant and major blocking of the EC process is observed from line profiles recorded as the SECCM meniscus moves over an SWNT. The SECCM line profile morphology is shown to be highly diagnostic of whether blocking occurs during EC processes. The studies herein add to a growing body of evidence that various EC processes at SWNTs, from simple outer sphere redox reactions to complex multi-step processes, occur readily at pristine SWNTs. The platform described is of general applicability to various types of nanostructures and nanowires.
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影响因子：
15
作者：
Gueell, Aleix G.;Ebejer, Neil;Unwin, Patrick R.
通讯作者：
Unwin, Patrick R.
影响因子：
10.8
作者：
Rodolfa, KT;Bruckbauer, A;Klenerman, D
通讯作者：
Klenerman, D
影响因子：
15
作者：
Bertoncello, Paolo;Edgeworth, Jonathan P.;Unwin, Patrick R.
通讯作者：
Unwin, Patrick R.
影响因子：
7.4
作者：
Harreither, Wolfgang;Trouillon, Raphael;Poulin, Philippe;Neri, Wilfrid;Ewing, Andrew G.;Safina, Gulnara
通讯作者：
Safina, Gulnara
DOI：
10.1146/annurev-anchem-062012-092650
发表时间：
2013-01-01
期刊：
ANNUAL REVIEW OF ANALYTICAL CHEMISTRY, VOL 6
影响因子：
--
作者：
Ebejer, Neil;Gueell, Aleix G.;Unwin, Patrick R.
通讯作者：
Unwin, Patrick R.