Defining ‘medical necessity’ in an age of personalised medicine: A view from Canada
Defining ‘medical necessity’ in an age of personalised medicine: A view from Canada
复制标题
个性化医疗时代的“医疗必要性”定义：加拿大的观点
DOI：
10.1002/bies.201400073
复制
发表时间：
2014
期刊：
影响因子：
4
通讯作者：
A. Zarzeczny
中科院分区：
文献类型：
--
作者：
T. Caulfield;A. Zarzeczny
医疗必要性的概念在包括加拿大在内的许多医疗保健系统中发挥着核心作用，有助于确定哪些医疗保健服务将获得资金。尽管医疗必要性在卫生政策框架中具有重要意义，但事实证明，医疗必要性非常难以定义和操作。向更加个性化和基因知情的方式转变提供医疗保健似乎可能会加剧相关的政策挑战。个性化医疗的既定目标之一是通过促进使用更少和更有效的治疗来节省医疗保健系统的资金。然而，任何节省成本的潜力最终都可能受到医生的法律的和道德义务的阻碍，因为医生将不可避免地被要求为他们的患者实施和定义遗传信息医疗必要性的界限。
The concept of medical necessity plays a central role in many healthcare systems, including Canada's, by helping determine which healthcare services will receive funding. Despite its significance in health policy frameworks, medical necessity has proven to be notoriously difficult to define and operationalise. A shift toward a more personalised and genetically‐informed approach to the provision of healthcare seems likely to heighten associated policy challenges. One of the stated goals of personalised medicine is to save healthcare systems money by facilitating the use of less and more effective treatments. However, any cost saving potential may ultimately be thwarted by physicians' legal and ethical obligations, given that physicians will inevitably be required to implement and define the bounds of genetically‐informed medical necessity for their patients.
DOI：
10.1056/nejmoa1310669
发表时间：
2013-12-12
期刊：
The New England journal of medicine
影响因子：
--
作者：
Kimmel SE;French B;Kasner SE;Johnson JA;Anderson JL;Gage BF;Rosenberg YD;Eby CS;Madigan RA;McBane RB;Abdel-Rahman SZ;Stevens SM;Yale S;Mohler ER 3rd;Fang MC;Shah V;Horenstein RB;Limdi NA;Muldowney JA 3rd;Gujral J;Delafontaine P;Desnick RJ;Ortel TL;Billett HH;Pendleton RC;Geller NL;Halperin JL;Goldhaber SZ;Caldwell MD;Califf RM;Ellenberg JH;COAG Investigators
通讯作者：
COAG Investigators
影响因子：
2.3
作者：
Flores M;Glusman G;Brogaard K;Price ND;Hood L
通讯作者：
Hood L
影响因子：
120.7
作者：
Dewey, Frederick E.;Grove, Megan E.;Pan, Cuiping;Goldstein, Benjamin A.;Bernstein, Jonathan A.;Chaib, Hassan;Merker, Jason D.;Goldfeder, Rachel L.;Enns, Gregory M.;David, Sean P.;Pakdaman, Neda;Ormond, Kelly E.;Caleshu, Colleen;Kingham, Kerry;Klein, Teri E.;Whirl-Carrillo, Michelle;Sakamoto, Kenneth;Wheeler, Matthew T.;Butte, Atul J.;Ford, James M.;Boxer, Linda;Ioannidis, John P. A.;Yeung, Alan C.;Altman, Russ B.;Assimes, Themistocles L.;Snyder, Michael;Ashley, Euan A.;Quertermous, Thomas
通讯作者：
Quertermous, Thomas