P4 medicine: how systems medicine will transform the healthcare sector and society.
P4 medicine: how systems medicine will transform the healthcare sector and society.
复制标题
DOI：
10.2217/pme.13.57
复制
发表时间：
2013
影响因子：
2.3
通讯作者：
Hood L
中科院分区：
文献类型：
--
作者：
Flores M;Glusman G;Brogaard K;Price ND;Hood L
十年前，医疗保健正在从反应性疾病护理演变为预测性，预防性，个性化和参与性护理的主张被认为是高度投机的。今天，这一愿景的核心要素被广泛接受，并在美国医学研究所最近的一系列报告中得到了阐述。生物学和医学的系统方法现在开始为患者、消费者和医生提供关于每个人在分子、细胞和器官水平上的健康和疾病的独特健康体验的个性化信息。这些信息将使疾病护理从根本上更具成本效益，通过个性化护理每个人的独特生物学和治疗的原因，而不是疾病的症状。它还将为消费者采取具体行动提供依据，以改善他们的健康，因为他们观察到生活方式决定的影响。在数字化家庭和亲和网络中共同努力，消费者将能够减少复杂慢性病的发病率，目前占美国疾病护理费用的75%。
Ten years ago, the proposition that healthcare is evolving from reactive disease care to care that is predictive, preventive, personalized and participatory was regarded as highly speculative. Today, the core elements of that vision are widely accepted and have been articulated in a series of recent reports by the US Institute of Medicine. Systems approaches to biology and medicine are now beginning to provide patients, consumers and physicians with personalized information about each individual’s unique health experience of both health and disease at the molecular, cellular and organ levels. This information will make disease care radically more cost effective by personalizing care to each person’s unique biology and by treating the causes rather than the symptoms of disease. It will also provide the basis for concrete action by consumers to improve their health as they observe the impact of lifestyle decisions. Working together in digitally powered familial and affinity networks, consumers will be able to reduce the incidence of the complex chronic diseases that currently account for 75% of disease-care costs in the USA.
登录
查看更多内容
影响因子：
6.9
作者：
Meisel, Susanne F.;Walker, Catherine;Wardle, Jane
通讯作者：
Wardle, Jane
影响因子：
30.8
作者：
Grant, SFA;Thorleifsson, G;Stefansson, K
通讯作者：
Stefansson, K
影响因子：
9.9
作者：
Hwang, Daehee;Lee, Inyoul Y.;Yoo, Hyuntae;Gehlenborg, Nils;Cho, Ji-Hoon;Petritis, Brianne;Baxter, David;Pitstick, Rose;Young, Rebecca;Spicer, Doug;Price, Nathan D.;Hohmann, John G.;DeArmond, Stephen J.;Carlson, George A.;Hood, Leroy E.
通讯作者：
Hood, Leroy E.
影响因子：
2.3
作者：
Juengst ET;Settersten RA Jr;Fishman JR;McGowan ML
通讯作者：
McGowan ML
DOI：
10.1038/nrg2857
发表时间：
2010-09
期刊：
Nature reviews. Genetics
影响因子：
--
作者：
通讯作者：
--