Preparation and adsorption properties of phospho‐L‐glutamic acid on hydroxyapatite
Preparation and adsorption properties of phospho‐L‐glutamic acid on hydroxyapatite
复制标题
磷酸化L-谷氨酸的制备及其在羟基磷灰石上的吸附性能
DOI：
10.1002/sia.3709
复制
发表时间：
2011
影响因子：
1.7
通讯作者：
Zhongjun Li
中科院分区：
文献类型：
--
作者：
Xiao‐qing Shen;Yuan;Xiao;M. Tang;Zhongjun Li
通过谷氨酸的磷酸化制备了磷酸-L-谷氨酸，并与谷氨酸一起研究了磷酸-L-谷氨酸在合成羟基磷灰石（HAP）上的吸附。两种吸附物的吸附行为均符合Langmuir模型。通过两种不同吸附物的比较，研究结果表明，磷酸-L-谷氨酸中的磷酸基团可以极大地提高HAP对HAP的吸附亲和力，这种提高是通过取代HAP表面的磷酸基团，并通过静电引力与HAP表面的钙离子相互作用实现的。研究结果为进一步研究磷酸化氨基酸对羟基磷灰石生物复合材料的调控作用奠定了基础。版权所有© 2010约翰威利父子有限公司.
Phospho‐L‐glutamic acid was successfully prepared by the phosphorylation of glutamic acid, and its adsorption on synthetic hydroxyapatite (HAP) was studied together with glutamic. The adsorption behaviors of both adsorbates were adequately described by a Langmuirian model. From the comparison between two different adsorbates, the results of the investigation indicated that the phosphate group in phospho‐L‐glutamic acid can greatly enhanced the adsorption affinity for HAP, the improvement of which was achieved through replacing the same group on the surface of HAP and interacting with the surface calcium ion of HAP by electrostatic attraction. The results obtained laid the solid foundation for further research on the regulating function of phosphorylated amino acids with hydroxyapatite biological composites. Copyright © 2010 John Wiley & Sons, Ltd.
影响因子：
14
作者：
Kikuchi, M;Itoh, S;Tanaka, J
通讯作者：
Tanaka, J