Imaging-guided nanomedicine development.

Imaging-guided nanomedicine development.
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DOI:
10.1016/j.cbpa.2021.01.014
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发表时间:
2021-08
影响因子:
7.8
通讯作者:
Pérez-Medina C
Pérez-Medina C
中科院分区:
生物学2区
文献类型:
--
作者:
Bernal A;Calcagno C;Mulder WJM;Pérez-Medina C

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Nanomedicine research is an active field that produces thousands of studies every year. However, translation of nanotherapeutics to the clinic has yet to catch up with such a vast output. In recent years, the need to better understand nanomedicines’ in vivo behavior has been identified as one of the major challenges for efficient clinical translation. In this context, non-invasive imaging offers attractive solutions to provide valuable information about nanomedicine biodistribution, pharmacokinetics, stability or therapeutic efficacy. Here, we review the latest imaging approaches employed in the development of therapeutic nanomedicines, discuss why these strategies bring added value along the translational pipeline, and give a perspective on future advances in the field.
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