Paranasal sinuses malignancies: A 12-year review of clinical characteristics.
Paranasal sinuses malignancies: A 12-year review of clinical characteristics.
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DOI：
10.4317/medoral.21170
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发表时间：
2016-09-01
期刊：
影响因子：
--
通讯作者：
Derakhshandeh H
中科院分区：
文献类型：
--
作者：
Danesh-Sani SA;Sarafraz A;Chamani M;Derakhshandeh H
对副鼻窦恶性肿瘤的流行病学调查不足促使了这项回顾研究，特别强调了主要的111种肿瘤。对2000年4月至2012年1月收治的111例经手术病理证实的副鼻窦恶性肿瘤患者的临床资料进行回顾性分析。收集的数据包括肿瘤的人口统计信息、临床表现、治疗计划和组织病理学。男69例(62.16%)，女42例(37.83%)，男女之比为1.6：1，年龄21~88岁，中位年龄49±12.2岁。在生命的第五个十年(26.3%)注意到高水平的发生。最常见的组织学类型是鳞癌(43.5%)和腺样囊性癌(19%)。在临床表现中，鼻塞最常见，其次是复视和面部肿胀。53例(47.74%)采用手术加放射治疗。副鼻窦恶性肿瘤是一种罕见的具有非特异性症状的疾病，这使得其早期诊断更具挑战性。对于患有这些肿瘤的患者的最佳治疗方案仍然是一个有一定争议的实体，需要进一步研究。关键词：副鼻窦，恶性肿瘤，外科，放射治疗。
Inadequate epidemiologic investigations of the paranasal sinuses malignancies prompted this retrospective study with special emphasis on a major group of 111 tumors. Clinical records of 111 patients with histologically confirmed malignant tumors of the paranasal sinuses were investigated retrospectively from April 2000 to January 2012. Collection of data included demographic information, clinical manifestations, treatment plans, and histopathology of the tumor. There were 69 (62.16%) male and 42 (37.83%) female patients (male-to-female ratio of 1.6:1), with a median age of 49±12.2 years (range 21 to 88 years). A high level of occurrence was noticed in the fifth (26.3%) decade of life. The most frequent histological types were squamous cell carcinoma (43.5%) and adenoid cystic carcinoma (19%). Among clinical manifestations, nasal obstruction was the most frequent followed by diplopia, and facial swelling. Fifty three patients (47.74%) were treated with combined approach of surgery and radiation therapy. Paranasal sinuses malignancies are rare conditions with nonspecific symptoms which make early diagnosis of the lesions more challenging. The optimal therapeutic protocol for patients suffering from these tumors is still a somewhat controversial entity and requires further studies. Key words:Paranasal sinuses, malignancy, surgery,radiotherapy.
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影响因子：
--
作者：
Mannu GS;Iyer NG;Shah J
通讯作者：
Shah J
DOI：
10.2500/ajr.2007.21.2957
发表时间：
2007-01-01
期刊：
AMERICAN JOURNAL OF RHINOLOGY
影响因子：
--
作者：
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通讯作者：
Wei, William I.
影响因子：
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作者：
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通讯作者：
Rossi, Marco
DOI：
10.1016/j.ijrobp.2003.09.101
发表时间：
2004-05-01
影响因子：
7
作者：
Blanco, AI;Chao, KSC;Perez, CA
通讯作者：
Perez, CA
影响因子：
1.8
作者：
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通讯作者：
Mohammadianpanah, Mohammad