Evaluation of Respiratory Symptoms Among Youth e-Cigarette Users.
Evaluation of Respiratory Symptoms Among Youth e-Cigarette Users.
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DOI：
10.1001/jamanetworkopen.2020.20671
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发表时间：
2020-10-01
影响因子：
13.8
通讯作者：
Wagener TL
中科院分区：
文献类型：
--
作者：
Tackett AP;Keller-Hamilton B;Smith CE;Hébert ET;Metcalf JP;Queimado L;Stevens EM;Wallace SW;McQuaid EL;Wagener TL
这项队列研究使用了2015年至2018年烟草与健康人口评估的数据，研究了青少年喘息与过去一年使用电子烟之间的关系。青少年的喘息与使用电子烟有关吗？在这项针对7049名青少年的队列研究中，在烟草与健康人口评估的第3和第4波中，在过去的12个月里，使用电子烟的青少年与没有使用电子烟的青少年相比，喘息的几率更高。在调整后的模型中，使用电子烟与喘息的关联不显著。研究结果表明，单独使用电子烟可能与喘息几率增加无关。近年来，青少年使用电子烟的人数有所增加。电子烟气雾剂含有化学成分，如二乙酰或苯甲醛，已知会影响呼吸系统。在一组美国青少年中，研究电子烟使用与自我报告的喘息之间的关系。这项队列研究使用了烟草与健康人口评估（PATH）研究的第三和第四波（2015年10月19日至2018年1月3日）的数据，这是一项纵向的、具有全国代表性的队列调查。12至17岁的青少年受访者包括没有哮喘的人。上一年电子烟的使用情况。自述过去12个月有或没有喘息现象，是否使用EC（过去一年没有使用或从未使用，过去一年使用，过去30天使用，过去7天使用）。调查加权逻辑回归模型调整人口统计学特征和其他危险因素。在PATH研究第3和第4阶段的7049名无哮喘青少年中，49.9%为女性，54.4%为非西班牙裔白人。在未调整的模型中，在过去12个月内使用ECs的青少年发生喘息的几率高于未使用ECs的青少年（优势比为1.74；95% CI为1.22-2.48;P = 0.003）。在调整模型中,在控制变量的种族/民族,家庭规则烟草的使用,与吸烟者接触前7天,和当前使用可燃烟草制品,电子商务协会使用喘息不显著(调整后的优势比EC使用在过去的一年中,1.37(95%可信区间,0.91 - -2.05);在过去的30天,1.35(95%可信区间,0.63 - -2.88);在过去的7天,0.74(95%可信区间,0.28 - -1.97);P = .33)。在这项队列研究中，单独使用ECs与发生喘息发作的几率增加无关。为了更准确地了解青少年吸电子烟对呼吸系统的潜在危害，未来的研究似乎需要结合客观数据。
This cohort study uses data from the Population Assessment of Tobacco and Health from 2015 to 2018 to examine the association between wheezing and past-year use of e-cigarettes among youths. Is wheezing associated with e-cigarette use among youths? In this cohort study of 7049 adolescents in waves 3 and 4 of the Population Assessment of Tobacco and Health, the odds of wheezing in the past 12 months were higher for adolescents who had used e-cigarettes during the past year compared with those who had not used e-cigarettes. In the adjusted model, the association of e-cigarette use with wheezing was not significant. The findings suggest that e-cigarette use alone might not be associated with increased odds of wheezing. Use of e-cigarettes (ECs) among youths has increased in recent years. e-Cigarette aerosol contains chemical constituents, such as diacetyl or benzaldehyde, which are known to affect the respiratory system. To examine the association between EC use and self-reported wheezing in a cohort of US adolescents. This cohort study used data from waves 3 and 4 (October 19, 2015, to January 3, 2018) of the Population Assessment of Tobacco and Health (PATH) study, a longitudinal, nationally representative cohort survey. Adolescent respondents aged 12 to 17 years who did not have asthma were included. e-Cigarette use during the previous year. Self-reported wheezing in the past 12 months (yes or no) and EC use (no use in past year or never use, use in past year, use in past 30 days, and use in past 7 days). Survey-weighted logistic regression models adjusted for demographic characteristics and other risk factors. Among 7049 adolescents without asthma from waves 3 and 4 of the PATH study, 49.9% were female and 54.4% were non-Hispanic White. In unadjusted models, the odds of wheezing in the past 12 months were higher for youths who had used ECs in the past year compared with those who had not (odds ratio, 1.74; 95% CI, 1.22-2.48; P = .003). In the adjusted model, after controlling for the variables of race/ethnicity, household rules about the use of tobacco, contact with a smoker in the previous 7 days, and current use of combustible tobacco products, the association of EC use with wheezing was not significant (adjusted odds ratio for EC use in the past year, 1.37 [95% CI, 0.91-2.05]; in the past 30 days, 1.35 [95% CI, 0.63-2.88]; in the past 7 days, 0.74 [95% CI, 0.28-1.97]; P = .33). In this cohort study, use of ECs alone was not associated with increased odds of experiencing wheezing episodes. Future studies incorporating the use of objective data appear to be needed to more accurately understand the potential respiratory harms associated with vaping among adolescents.
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电子烟的使用与青春期早期燃烧烟草产品吸烟的启动。
DOI：
10.1001/jama.2015.8950
发表时间：
2015-08-18
期刊：
JAMA
影响因子：
--
作者：
Leventhal AM;Strong DR;Kirkpatrick MG;Unger JB;Sussman S;Riggs NR;Stone MD;Khoddam R;Samet JM;Audrain-McGovern J
通讯作者：
Audrain-McGovern J
影响因子：
10.4
作者：
Allen JG;Flanigan SS;LeBlanc M;Vallarino J;MacNaughton P;Stewart JH;Christiani DC
通讯作者：
Christiani DC
影响因子：
5.2
作者：
Hyland, Andrew;Ambrose, Bridget K.;Compton, Wilson M.
通讯作者：
Compton, Wilson M.
影响因子：
3.2
作者：
Bishop, E.;Haswell, L.;Gaca, M.
通讯作者：
Gaca, M.
影响因子：
26.1
作者：
Primack, Brian A.;Soneji, Samir;Sargent, James D.
通讯作者：
Sargent, James D.