Thomas E. Starzl, MD, PhD: Father of Transplantation-March 11, 1926-March 4, 2017.
Thomas E. Starzl, MD, PhD: Father of Transplantation-March 11, 1926-March 4, 2017.
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Thomas E. Starzl，医学博士、博士：移植之父-1926年3月11日-2017年3月4日。
作者：
Yu Toyoda;Tappei Takada;and Hiroshi Suzuki;Ueno T
1977年，国际人工器官学会推出了第一期官方出版物《Artificial Organs》。第一期二十年后，我们收到了一位移植外科医生发表的题为“器官移植后细胞迁移和微嵌合现象的临床和基本科学意义”的文章 (1)。该文章阐明了“器官移植后的双向范式：整个器官的宿主抗移植物（HVG）和移植物抗宿主（GVH）作为细胞迁移和微嵌合的科学意义。”最近，这一概念已在该领域被接受 (2)（1215 次引用），并指导我们当前使用 FK506、环孢菌素和类固醇疗法等免疫抑制药物的移植医学 (3, 4)。 1996 年，为了纪念移植外科医生，匹兹堡大学的移植研究所更名为托马斯·E·斯塔兹尔移植研究所 (STI)。该研究所在世界各地享有盛誉，一直是致力于帮助终末期器官衰竭患者的领先国际资源。由于我的同事在该研究所拥有研究和临床经验，STI 带来了多个学科的专业知识，包括免疫学、外科、病理学、肾病学、肝病学、分子生物学、遗传学和细胞生理学，以改善移植的临床、科学和社会方面 (http://stiresearch.health.pitt.edu/about)。 Thomas Starzl（又名 Tommie）于 1926 年 3 月 11 日出生于美国爱荷华州勒马尔斯。从美国密苏里州富尔顿威斯敏斯特学院毕业后，他在西北大学获得医学博士和博士学位（神经科学）（1952 年）。双学位毕业后，他在巴尔的摩约翰·霍普金斯医院实习。在约翰·霍普金斯大学接受研究生外科培训期间（1952-1956 年），Starzl 医生获得了普通外科、血管外科和胸外科的广泛技能。随后，他在一流的大学医院开始了自己的外科教师生涯。 Starzl 博士于 1981 年加入匹兹堡大学医学院，担任外科教授，并领导外科医生团队进行了匹兹堡首例肝脏移植手术。然后，该遗产开始在大学发展多器官移植项目。
In 1977, the International Society for Artificial Organs launched the first issue of its official publication as Artificial Organs. Twenty years after the first issue, we received an article entitled “Clinical and Basic Scientific Implications of Cell Migration and Microchimerism After Organ Transplantation” from a transplant surgeon (1). The article shed light on “the 2-way paradigm after organ transplantation: host-versus-graft (HVG) with whole organs and graft-versus-host (GVH) as scientific implications of cell migration and microchimerism.” Recently, the concept has been accepted in the field (2)(1215 citations) and has guided us to current transplant medicine using immunosuppression drugs such as FK506, cyclosporine, and steroid therapy (3, 4). At theUniversity of Pittsburgh the Transplantation Institute was renamed the Thomas E. Starzl Transplantation Institute (STI) in 1996 in honor of the transplant surgeon. The institute is well known all over the world and has been a leading international resource dedicated to helping people with end-stage organ failure. As my colleagues had research and clinical experiences at the institute, the STI brings expertise from multiple disciplines including immunology, surgery, pathology, nephrology, hepatology, molecular biology, genetics, and cell physiology to improve the clinical, scientific, and social aspects of transplantation (http://stiresearch. health. pitt. edu/about). Thomas Starzl (called Tommie) was born on March 11, 1926, in LeMars, IA, USA. After graduating from Westminster College in Fulton, MO, USA he earned a MD and PhD (neuroscience) degrees at Northwestern University (1952). The double graduation was followed by an internship at the Johns Hopkins Hospital in Baltimore. During his years of post-graduate surgical training at Johns Hopkins (1952–1956), Dr. Starzl acquired a widerange of skills in general, vascular, and thoracic surgery. He then built his surgical faculty career at top-ranked university hospitals. Dr. Starzl joined the University of Pittsburgh School of Medicine in 1981 as professor of surgery and led the team of surgeons who performed Pittsburgh’s first liver transplant. And then the legacy began in the development of a multiple organ transplantation program at the University.
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DOI：
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发表时间：
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期刊：
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影响因子：
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影响因子：
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影响因子：
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DOI：
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发表时间：
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影响因子：
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作者：
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影响因子：
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作者：
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通讯作者：
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