Insertional mutagenesis strategies in zebrafish.
Insertional mutagenesis strategies in zebrafish.
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DOI:
10.1186/gb-2007-8-s1-s9
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发表时间:
2007
期刊:
影响因子:
12.3
通讯作者:
Ekker SC
中科院分区:
文献类型:
--
作者:
Sivasubbu S;Balciunas D;Amsterdam A;Ekker SC
We review here some recent developments in the field of insertional mutagenesis in zebrafish. We highlight the advantages and limitations of the rich body of retroviral methodologies, and we focus on the mechanisms and concepts of new transposon-based mutagenesis approaches under development, including prospects for conditional 'gene trapping' and 'gene breaking' approaches.
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