Fine-Needle Aspiration Biopsy of Pediatric Salivary Gland Tumors: Analysis of Patient Tolerability, Sedation Requirement, and Procedural Complication.
Fine-Needle Aspiration Biopsy of Pediatric Salivary Gland Tumors: Analysis of Patient Tolerability, Sedation Requirement, and Procedural Complication.
复制标题
细针吸入活检对小儿唾液腺肿瘤：分析患者的耐受性，镇静需求和程序并发症。
作者：
细针抽吸（FNA）活检是共识管理指南推荐的成人涎腺肿瘤术前评估的标准诊断工具。然而，由于缺乏数据和儿科管理的固有挑战（患者合作、镇静需求和手术并发症），其在儿科人群中的效用仍存在争议。对92例儿童涎腺病变的连续FNA活检进行回顾性分析。对患者人口统计学资料、手术特征和并发症进行了评估。63例患者（68%）耐受FNA，无镇静作用。镇静需求与年龄较小、需要镇静的并发非FNA手术、超声引导、介入放射科医生作为手术医师以及放射科套房作为设施设置显著相关。儿童、早期、中期和晚期青少年的镇静率分别为69%、32%、12%和10%，根据受试者工作特征曲线分析得出的年龄最佳临界点为≤12岁。未观察到明显的手术并发症。镇静并没有提供显着更好的诊断率。涎腺肿瘤的细针穿刺活检是安全的，儿科人群耐受性良好，并且在大多数情况下可以在门诊环境中有效地进行而无需镇静。细针穿刺活检是一个有用的工具，在术前管理的儿童涎腺肿瘤患者。
Fine-needle aspiration (FNA) biopsy is the standard diagnostic tool recommended by consensus management guidelines for preoperative evaluation of salivary gland tumors in adults. However, its utility in the pediatric population remains debated due to a paucity of data and inherited challenges of pediatric management (patient cooperation, the need for sedation, and procedural complications). Consecutive series of 92 FNA biopsies of pediatric salivary gland lesions with available procedural data were included for retrospective analysis. Patient demographics, procedural characteristics and complications were assessed. Sixty-three patients (68%) tolerated FNA without sedation. Sedation need was significantly associated with younger age, concurrent non-FNA procedure requiring sedation, ultrasound guidance, interventional radiologist as the proceduralist, and radiology suite as the facility setting. The sedation rates for children, early, middle, and late adolescents were 69%, 32%, 12%, and 10%, respectively, with an optimal cutoff point of ≤12 years for age derived from Receiver Operating Characteristic curve analysis. No significant procedural complications were observed. Sedation did not provide significantly better diagnostic yield. FNA biopsy of salivary gland tumors is safe, well-tolerated by the pediatric population, and can be effectively performed in an outpatient setting without sedation in most cases. FNA biopsy is a useful tool in the preoperative management of pediatric patients with salivary gland tumors.
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DOI：
10.1016/j.ijporl.2008.07.009
发表时间：
2008-10-01
影响因子：
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