Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children.
Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children.
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DOI：
10.1016/j.neuroimage.2022.119027
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发表时间：
2022-05-15
期刊：
影响因子：
5.7
通讯作者：
Brookes, Matthew J.
中科院分区：
文献类型：
--
作者：
Boto, Elena;Shah, Vishal;Hill, Ryan M.;Rhodes, Natalie;Osborne, James;Doyle, Cody;Holmes, Niall;Rea, Molly;Leggett, James;Bowtell, Richard;Brookes, Matthew J.
光泵磁力计（OPM）是脑磁图（MEG）超导传感器的既定替代方案，具有显著的优势，包括适应任何头部尺寸的灵活性，均匀的覆盖范围，扫描期间的自由移动，更好的数据质量和更低的成本。然而，OPM传感器技术仍在开发中; OPM设计具有灵活性，目前尚不清楚哪种变体对MEG最有效。大多数OPM-MEG实现都使用单轴（相当于传统的MEG）或双轴磁场测量。在这里，我们展示了使用三轴OPM配方，能够模拟完整的3D神经磁场矢量。我们表明，这种新型的传感器是能够以高精度和灵敏度，匹配传统的（双轴）OPM的磁场。我们通过测量心脏和大脑的生物磁场来展示实用性。使用模拟，我们演示了如何三轴测量提供了改进的皮质覆盖，特别是在婴儿。最后，我们介绍了一种新的3D打印的儿童友好型OPM头盔，并证明了五岁儿童三轴测量的可行性。总之，所提供的数据表明，三轴OPM提供了一个显着的改进，双轴的变种，并有可能成为未来的MEG系统的传感器的选择，特别是在儿科人群的部署。
Optically-pumped magnetometers (OPMs) are an established alternative to superconducting sensors for magnetoencephalography (MEG), offering significant advantages including flexibility to accommodate any head size, uniform coverage, free movement during scanning, better data quality and lower cost. However, OPM sensor technology remains under development; there is flexibility regarding OPM design and it is not yet clear which variant will prove most effective for MEG. Most OPM-MEG implementations have either used single-axis (equivalent to conventional MEG) or dual-axis magnetic field measurements. Here we demonstrate use of a triaxial OPM formulation, able to characterise the full 3D neuromagnetic field vector. We show that this novel sensor is able to characterise magnetic fields with high accuracy and sensitivity that matches conventional (dual-axis) OPMs. We show practicality via measurement of biomagnetic fields from both the heart and the brain. Using simulations, we demonstrate how triaxial measurement offers improved cortical coverage, especially in infants. Finally, we introduce a new 3D-printed child-friendly OPM-helmet and demonstrate feasibility of triaxial measurement in a five-year-old. In sum, the data presented demonstrate that triaxial OPMs offer a significant improvement over dual-axis variants and are likely to become the sensor of choice for future MEG systems, particularly for deployment in paediatric populations.
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在头皮安装的磁刻摄影术中用于无效背景磁场的双平面线圈系统。
影响因子：
5.7
作者：
Holmes N;Leggett J;Boto E;Roberts G;Hill RM;Tierney TM;Shah V;Barnes GR;Brookes MJ;Bowtell R
通讯作者：
Bowtell R
影响因子：
5.7
作者：
Iivanainen J;Stenroos M;Parkkonen L
通讯作者：
Parkkonen L
影响因子：
--
作者：
Oostenveld R;Fries P;Maris E;Schoffelen JM
通讯作者：
Schoffelen JM
影响因子：
56.9
作者：
COHEN, D
通讯作者：
COHEN, D
影响因子：
16.6
作者：
Hill, Ryan M.;Boto, Elena;Brookes, Matthew J.
通讯作者：
Brookes, Matthew J.