The relationship between education level and mini-mental state examination domains among older Mexican Americans.

The relationship between education level and mini-mental state examination domains among older Mexican Americans.
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DOI:
10.1177/0891988710373597
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发表时间:
2011-03
影响因子:
2.6
通讯作者:
Reyes-Ortiz CA
Reyes-Ortiz CA
中科院分区:
医学4区
文献类型:
--
作者:
Matallana D;de Santacruz C;Cano C;Reyes P;Samper-Ternent R;Markides KS;Ottenbacher KJ;Reyes-Ortiz CA

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为了研究教育对简易精神状态检查(MMSE)领域表现的影响,我们纳入了2,861名65岁及以上的墨西哥裔美国人,他们来自1993-1994年至2004-2005年的西班牙裔老年人流行病学研究(EPESE)人群。MMSE检查为总分(0-30)或分为两个整体领域:1)无记忆(评分0-24):定向、注意力和语言; 2)记忆(评分0-6):工作记忆和延迟记忆。第1波的平均年龄和总MMSE分别为72.7和24.6,第5波为81.7和20.5。西班牙语受试者的受教育年限较低(4.1 vs. 7.4,p<.0001),在五波随访中,与英语受试者相比,西班牙语受试者的记忆、无记忆和总MMSE的调整后(按年龄、教育和性别)平均得分显著较高。在11年的多变量纵向分析中,受教育年限越长的受试者表现越好,尤其是在无记忆和总MMSE方面。受教育4-6年的西班牙语受试者的记忆得分高于英语受试者(估计值0.40,标准误[SE] = 0.14,p<.001),7-11(估计值0.27,SE= 0.13,p<.01)或12+(估计值0.44,SE= 0.13,p<.001)。这表明,文化因素和因素相关的首选语言使用可能会决定MMSE性能的变化。由于MMSE的记忆域受教育程度的影响较小,因此它可以沿着其他认知测试用于受教育程度较低的老年人群。
To study the effect of education on the performance in the Mini-Mental State Examination (MMSE) domains, we included 2,861 Mexican Americans aged 65 and older from the Hispanic Established Populations for Epidemiologic Studies of the Elderly (EPESE) followed from 1993–1994 until 2004–2005. The MMSE was examined as total score (0–30) or divided in two global domains: 1) no-memory (score 0–24): Orientation, attention, and language; and 2) memory (score 0–6): working and delayed memory. Mean age and total MMSE were 72.7 and 24.6 at wave 1, and 81.7 and 20.5 at wave 5. Spanish speaking subjects had lower years of education (4.1 vs. 7.4, p<.0001), they had significantly higher adjusted (by age, education, and gender) mean scores for memory, no-memory and the total MMSE compared with English speaking subjects across the five waves of follow-up. In multivariate longitudinal analyses over 11 years of follow-up, subjects with more years of education performed better than those less educated, especially in no-memory and the total MMSE. Spanish speaking subjects with 4–6 years of education had higher memory scores than those speaking English (estimate 0.40, standard error [SE] = 0.14, p<.001), 7–11 (estimate 0.27, SE= 0.13, p<.01) or 12+ (estimate 0.44, SE= 0.13, p<.001). This suggests that cultural factors and factors related to preferred language use may determine variations in MMSE performance. Since the memory domain of the MMSE is less affected by education, it may be used along with other cognitive tests in older populations with low education.
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