Extending the Human Connectome Project across ages: Imaging protocols for the Lifespan Development and Aging projects.
Extending the Human Connectome Project across ages: Imaging protocols for the Lifespan Development and Aging projects.
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扩展人类连接项目跨越时代：寿命开发和衰老项目的成像协议。
DOI：
10.1016/j.neuroimage.2018.09.060
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发表时间：
2018-12
期刊：
影响因子：
5.7
通讯作者：
Yacoub E
中科院分区：
文献类型：
--
作者：
Harms MP;Somerville LH;Ances BM;Andersson J;Barch DM;Bastiani M;Bookheimer SY;Brown TB;Buckner RL;Burgess GC;Coalson TS;Chappell MA;Dapretto M;Douaud G;Fischl B;Glasser MF;Greve DN;Hodge C;Jamison KW;Jbabdi S;Kandala S;Li X;Mair RW;Mangia S;Marcus D;Mascali D;Moeller S;Nichols TE;Robinson EC;Salat DH;Smith SM;Sotiropoulos SN;Terpstra M;Thomas KM;Tisdall MD;Ugurbil K;van der Kouwe A;Woods RP;Zöllei L;Van Essen DC;Yacoub E
人类连接组开发项目（HCP-D）和衰老（HCP-A）是两项大规模的脑成像研究，将最近完成的HCP年轻成人（HCP-YA）项目扩展到几乎整个生命周期，收集5至100岁以上参与者的结构，静息状态fMRI，任务fMRI，扩散和灌注MRI。HCP-D正在招募1300多名健康儿童、青少年和年轻成人（5-21岁），HCP-A正在招募1200多名健康成人（36-100岁），每项研究均收集特定年龄范围个体子集的纵向数据。HCP-D和HCP-A研究的成像方案非常相似，主要区别在于选择了不同的任务-fMRI范式。我们努力在可行的最大程度上使成像方案与已完成的HCP-YA（1200多名参与者，年龄22-35岁）相协调，但一些成像相关变更的动机或必要性是硬件变更、减少每位参与者扫描总量的需求和/或与年轻和老年人群一起工作的额外挑战。在此，我们提供了常见HCP-D/A成像方案的概述，包括与HCP-YA相关的方案决策和变更的数据和依据。其结果将是一个大的，丰富的，多模态的，和免费提供的一组一致获得的数据，供科学界使用，以调查和定义规范的发展和衰老相关的变化，在健康的人类大脑。
The Human Connectome Projects in Development (HCP-D) and Aging (HCP-A) are two large-scale brain imaging studies that will extend the recently completed HCP Young-Adult (HCP-YA) project to nearly the full lifespan, collecting structural, resting-state fMRI, task-fMRI, diffusion, and perfusion MRI in participants from 5 to 100+ years of age. HCP-D is enrolling 1300+ healthy children, adolescents, and young adults (ages 5–21), and HCP-A is enrolling 1200+ healthy adults (ages 36–100+), with each study collecting longitudinal data in a subset of individuals at particular age ranges. The imaging protocols of the HCP-D and HCP-A studies are very similar, differing primarily in the selection of different task-fMRI paradigms. We strove to harmonize the imaging protocol to the greatest extent feasible with the completed HCP-YA (1200+ participants, aged 22–35), but some imaging- related changes were motivated or necessitated by hardware changes, the need to reduce the total amount of scanning per participant, and/or the additional challenges of working with young and elderly populations. Here, we provide an overview of the common HCP-D/A imaging protocol including data and rationales for protocol decisions and changes relative to HCP-YA. The result will be a large, rich, multi-modal, and freely available set of consistently acquired data for use by the scientific community to investigate and define normative developmental and aging related changes in the healthy human brain.
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影响因子：
4.8
作者：
Geerligs L;Tsvetanov KA;Cam-Can;Henson RN
通讯作者：
Henson RN
DOI：
10.1523/jneurosci.2180-11.2011
发表时间：
2011-08-10
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Glasser MF;Van Essen DC
通讯作者：
Van Essen DC
影响因子：
5.7
作者：
Dosenbach NUF;Koller JM;Earl EA;Miranda-Dominguez O;Klein RL;Van AN;Snyder AZ;Nagel BJ;Nigg JT;Nguyen AL;Wesevich V;Greene DJ;Fair DA
通讯作者：
Fair DA
影响因子：
4.4
作者：
Biagi, Laura;Abbruzzese, Arturo;Tosetti, Michela
通讯作者：
Tosetti, Michela
影响因子：
25
作者：
Glasser MF;Smith SM;Marcus DS;Andersson JL;Auerbach EJ;Behrens TE;Coalson TS;Harms MP;Jenkinson M;Moeller S;Robinson EC;Sotiropoulos SN;Xu J;Yacoub E;Ugurbil K;Van Essen DC
通讯作者：
Van Essen DC