The Densities of Visceral Organs and the Extent of Pathologic Changes

The Densities of Visceral Organs and the Extent of Pathologic Changes
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内脏器官的密度与病理变化的程度

DOI:
10.1097/paf.0b013e3181875ab2
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发表时间:
2009-06
影响因子:
1
通讯作者:
Bai, Rufeng
Bai, Rufeng
中科院分区:
医学4区
文献类型:
--
作者:
Lv, Junyao;Lai, Xiaoping;Wang, Dian;Yu, Xiaojun;Xu, Guangtao;Bai, Rufeng

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本研究设计了一种新的脏器密度测量装置,并将其与脏器的病理变化进行了相关性研究。本文应用体积密度仪对169例尸检标本的心、肝、肺、脑等不同程度的病理改变进行了密度测量。所有标本分为2组:正常组和病理组。根据组织学特征将病变程度分为轻度水肿、中度水肿、重度水肿(或仅肝脏重度脂肪变性)3期。结果表明,各亚组与正常组相比,其密度差异有统计学意义,且密度与病理改变密切相关。因此,密度这一外部参数可能为脑水肿、脂肪变性等病理变化提供线索。
In this study, we designed a new device to measure the density of internal organs and correlated with their pathologic changes. The densities of hearts, livers, lungs and brains from 169 autopsy cases were measured with different extent of pathologic changes by an integrated volume-density meter. All samples were divided into 2 groups: intact and pathologic groups. The extent of pathologic changes was classified into 3 stages: slight edema, intermediate edema, severe edema (or severe fatty degeneration only for livers) according to the histologic features. Results show that there were significant differences between each subgroup and intact group and the density was closely correlated with pathologic changes. Therefore, the external parameter of density might offer some clues to its pathologic changes, such as edema and fatty changes.
DOI: --
发表时间: 2000-09
期刊: Aviation, space, and environmental medicine
影响因子: --
作者:
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