Clinical application of computed tomography in differential diagnosis of malignant and benign lesions in maxilla
Clinical application of computed tomography in differential diagnosis of malignant and benign lesions in maxilla
复制标题
CT在上颌骨良恶性病变鉴别诊断中的临床应用
DOI：
--
复制
发表时间：
2016-06
期刊：
影响因子：
--
通讯作者：
陶晓峰
中科院分区：
文献类型：
--
作者：
袁瑛;王晶波;吴颖为;李国俊;陶晓峰
我们的目的是确定最有用的计算机断层扫描(CT)特征，以区分恶性上颌骨肿瘤(MMTs)和良性上颌骨病变(BML)。对经组织病理证实、未经治疗的上颌骨病变患者的CT表现进行了回顾分析。采用Logistic回归分析评价CT征象与肿瘤恶性程度的关系。根据5个CT特征的总分将患者分为3组。我们确定了159名MMT患者和132名BML患者。经多因素分析，恶性黑色素瘤患者的皮质破坏和软组织伸展的可能性仍然高于骨髓瘤患者(优势比[OR]，49.9，95%可信区间[CI]分别为4.4~560.5和OR，17.5，95%CI，6.9~44.3)。与CT总分<lt；2相比，≥评分为4分和2分的患者发生多发性骨髓瘤的可能性分别是后者的20倍和430倍(OR分别为20.1，95%CI和430.5，95%CI，87.6%和2015.7)。CT为鉴别上颌骨良恶性病变提供了有价值的信息，尤其是皮质受累和软组织侵犯的存在。多参数CT扫描的价值可大大提高此类鉴别诊断的准确性。需要更大规模的研究来验证我们的发现。
Our aim was to identify the computed tomographic (CT) characteristics most useful to differentiate malignant maxillary tumors (MMTs) from benign maxillary lesions (BML). A retrospective review of CT findings was performed in patients with histopathologically confirmed, untreated maxillary lesions. Logistic regression analysis was performed to evaluate the associations between CT characteristics and malignancy. Patients were divided into three groups according to the summed scores of five CT characteristics. We identified 159 patients with MMT and 132 patients with BML. After multivariable analyses, patients with MMT remained more likely to have cortical destruction and soft tissue extension than those with BML (odds ratio [OR], 49.9, 95% confidence interval [CI], 4.4-560.5 and OR, 17.5, 95% CI, 6.9-44.3, respectively). Compared with a summed CT score of < 2, patients with a score of 2-4 and ≥ 4 were 20 and 430 times more likely to have MMT (OR, 20.1, 95% CI, 4.3-94.7 and OR, 430.5, 95% CI, 87.6-2015.7, respectively). CT provides valuable information about differentiating malignant and benign maxillary lesions, particularly the presence of cortical involvement and soft tissue extension. The value of multi-parametric CT may highly increase such a differential diagnosis. Larger studies are needed to validate our findings.
登录
查看更多内容
DOI：
10.1016/0895-6111(92)90193-d
发表时间：
1992
期刊：
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
影响因子：
--
作者：
H. Mast;J. Haller;M. Solomon
通讯作者：
H. Mast;J. Haller;M. Solomon
DOI：
10.1016/0030-4220(94)90331-x
发表时间：
1994-06-01
影响因子：
--
作者：
DARE, A;YAMAGUCHI, A;OKANO, T
通讯作者：
OKANO, T
影响因子：
2.7
作者：
Z. Neyaz;Ankur Gadodia;S. Gamanagatti;S. Mukhopadhyay
通讯作者：
Z. Neyaz;Ankur Gadodia;S. Gamanagatti;S. Mukhopadhyay
TNF-α启动子中的遗传变异是明确放疗后口咽鳞状细胞癌患者复发的预测指标。
影响因子：
6.4
作者：
Zhang, Caiyun;Sturgis, Erich M.;Zheng, Hongliang;Song, Xicheng;Wei, Peng;Jin, Lei;Chao, Li;Wei, Qingyi;Li, Guojun
通讯作者：
Li, Guojun
影响因子：
3.3
作者：
Ida, M.;Tetsumura, A.;Kurabayashi, T.
通讯作者：
Kurabayashi, T.