Chronological age, biological age, and individual variation in the stress response in the European starling: a follow-up study.
Chronological age, biological age, and individual variation in the stress response in the European starling: a follow-up study.
复制标题
作者：
Gott A;Andrews C;Larriva Hormigos M;Spencer K;Bateson M;Nettle D
鸟类应激反应的强度随着年龄的增长而下降。最近发表的一项关于欧洲椋鸟（Sturnus vulgaris）的研究发现，生物学年龄的标志物可以预测压力反应的强度，即使是在相同实际年龄的个体中。具体而言，经历了更大的发育端粒磨损（DTA）的鸟类表现出较低的峰值皮质酮（CORT）的急性应激反应，和更快的恢复CORT水平向基线。在这里，我们进行了一项后续研究，使用相同的捕获处理约束压力源在一个单独的队列的椋鸟，已受到发展操纵的食物供应和乞讨的努力。我们在两个不同的年龄点（4个月和18个月）测量了CORT反应。我们的数据表明CORT反应的强度随实际年龄的下降：峰值CORT在第二个年龄点较低，15和30分钟之间CORT的减少相对较多。两个年龄点之间的个体一致性较低，但基线和峰值CORT有适度的家族效应。乞讨努力的操纵影响的压力反应（具体来说，减少CORT之间的15和30分钟）的年龄依赖性的方式。然而，我们没有复制早期研究中观察到的与DTA的关联。我们对本研究和早期研究的数据进行了荟萃分析，发现了一些支持早期论文结论的证据。
The strength of the avian stress response declines with age. A recently published study of European starlings (Sturnus vulgaris) found that a marker of biological age predicted the strength of the stress response even in individuals of the same chronological age. Specifically, birds that had experienced greater developmental telomere attrition (DTA) showed a lower peak corticosterone (CORT) response to an acute stressor, and more rapid recovery of CORT levels towards baseline. Here, we performed a follow-up study using the same capture-handling-restraint stressor in a separate cohort of starlings that had been subjected to a developmental manipulation of food availability and begging effort. We measured the CORT response at two different age points (4 and 18 months). Our data suggest a decline in the strength of the CORT response with chronological age: peak CORT was lower at the second age point, and there was relatively more reduction in CORT between 15 and 30 min. Individual consistency between the two age points was low, but there were modest familial effects on baseline and peak CORT. The manipulation of begging effort affected the stress response (specifically, the reduction in CORT between 15 and 30 min) in an age-dependent manner. However, we did not replicate the associations with DTA observed in the earlier study. We meta-analysed the data from the present and the earlier study combined, and found some support for the conclusions of the earlier paper.
登录
查看更多内容
影响因子：
10.1
作者：
Fidler F;Chee YE;Wintle BC;Burgman MA;McCarthy MA;Gordon A
通讯作者：
Gordon A
影响因子：
5.2
作者：
Heidinger, Britt J.;Chastel, Olivier;Ketterson, Ellen D.
通讯作者：
Ketterson, Ellen D.
影响因子：
2.9
作者：
Bauer, Carolyn M.;Graham, Jessica L.;Greives, Timothy J.
通讯作者：
Greives, Timothy J.
DOI：
10.1098/rspb.2014.1610
发表时间：
2015-01-07
期刊：
Proceedings. Biological sciences
影响因子：
--
作者：
Nettle D;Monaghan P;Gillespie R;Brilot B;Bedford T;Bateson M
通讯作者：
Bateson M
影响因子：
3.3
作者：
Lendvai, Adam Z.;Giraudeau, Mathieu;Chastel, Olivier
通讯作者：
Chastel, Olivier