Ecological dynamics of plasmid transfer and persistence in microbial communities.

Ecological dynamics of plasmid transfer and persistence in microbial communities.
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DOI:
10.1016/j.mib.2022.102152
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发表时间:
2022-08
影响因子:
5.4
通讯作者:
Bottery, Michael J.
Bottery, Michael J.
中科院分区:
生物学2区
文献类型:
--
作者:
Bottery, Michael J.

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在原核生物中,质粒是水平基因转移的主要驱动力,允许在遥远的相关细菌类群之间共享生态上重要的附属特征。在微生物群落内,接合质粒的种间转移可以迅速推动世代基因组的创新和多样化。最近的研究开始揭示微生物群落环境,即细菌多样性以及群落内发生的物种间相互作用,如何改变接合质粒转移和持久性的动态。在这里,我总结了最新的研究,探索群落生态学如何促进和阻碍复杂微生物群落内接合质粒的传播。归根结底,质粒在群落中的命运不太可能由任何一个单独的宿主决定,而是取决于它所在的群落强加的相互作用的因素。
Plasmids are a major driver of horizontal gene transfer in prokaryotes, allowing the sharing of ecologically important accessory traits between distantly related bacterial taxa. Within microbial communities, interspecies transfer of conjugative plasmids can rapidly drive the generation genomic innovation and diversification. Recent studies are starting to shed light on how the microbial community context, that is, the bacterial diversity together with interspecies interactions that occur within a community, can alter the dynamics of conjugative plasmid transfer and persistence. Here, I summarise the latest research exploring how community ecology can both facilitate and impose barriers to the spread of conjugative plasmids within complex microbial communities. Ultimately, the fate of plasmids within communities is unlikely to be determined by any one individual host, rather it will depend on the interacting factors imposed by the community in which it is embedded.
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