Biodegradability engineering of biodegradable Mg alloys: tailoring the electrochemical properties and microstructure of constituent phases.

Biodegradability engineering of biodegradable Mg alloys: tailoring the electrochemical properties and microstructure of constituent phases.
复制标题

DOI:
10.1038/srep02367
复制
发表时间:
2013
期刊:
影响因子:
4.6
通讯作者:
Seok, Hyun-Kwang
Seok, Hyun-Kwang
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Cha, Pil-Ryung;Han, Hyung-Seop;Yang, Gui-Fu;Kim, Yu-Chan;Hong, Ki-Ha;Lee, Seung-Cheol;Jung, Jae-Young;Ahn, Jae-Pyeong;Kim, Young-Yul;Cho, Sung-Youn;Byun, Ji Young;Lee, Kang-Sik;Yang, Seok-Jo;Seok, Hyun-Kwang

文献摘要

参考文献

被引文献

相似文献

通过电化学和组织工程相结合的方法,制备了析氢明显减少的晶态镁基合金。在镁钙合金中添加锌改变了两个组成相(镁+镁钙)的腐蚀电位,防止了原电路的形成,并获得了与高纯镁相当的腐蚀速率。此外,挤压引起的有效的晶粒细化使腐蚀速率比高纯镁低得多。动物研究证实了氢气释放的大幅减少,并显示出与新开发的镁合金植入物周围骨沉积增加的良好组织相容性。因此,具有医学上可接受的腐蚀速率的高强度镁钙锌合金被开发出来,并在新一代可生物降解植入物中显示出巨大的潜力。
Crystalline Mg-based alloys with a distinct reduction in hydrogen evolution were prepared through both electrochemical and microstructural engineering of the constituent phases. The addition of Zn to Mg-Ca alloy modified the corrosion potentials of two constituent phases (Mg + Mg2Ca), which prevented the formation of a galvanic circuit and achieved a comparable corrosion rate to high purity Mg. Furthermore, effective grain refinement induced by the extrusion allowed the achievement of much lower corrosion rate than high purity Mg. Animal studies confirmed the large reduction in hydrogen evolution and revealed good tissue compatibility with increased bone deposition around the newly developed Mg alloy implants. Thus, high strength Mg-Ca-Zn alloys with medically acceptable corrosion rate were developed and showed great potential for use in a new generation of biodegradable implants.
DOI: 10.4028/www.scientific.net/kem.254-256.447
发表时间: 2004-01-01
期刊: BIOCERAMICS 16
影响因子: --
作者:
Revell, PA;Damien, E;Howlett, CR
通讯作者: Howlett, CR
DOI: 10.1103/physrevb.54.11169
发表时间: 1996-10-15
期刊: PHYSICAL REVIEW B
影响因子: 3.7
作者:
Kresse, G;Furthmuller, J
通讯作者: Furthmuller, J
二元镁合金的体外腐蚀与生物相容性
DOI: 10.1016/j.biomaterials.2008.10.021
发表时间: 2009-02-01
期刊: BIOMATERIALS
影响因子: 14
作者:
Gu, Xuenan;Zheng, Yufeng;Xi, Tingfei
通讯作者: Xi, Tingfei
DOI: 10.1080/17482960801934015
发表时间: 2008-01-01
影响因子: --
作者:
Post, Joan Isabel;Eibl, Joseph Karl;Ross, Gregory Michiel
通讯作者: Ross, Gregory Michiel
DOI: 10.1097/01.blo.0000096810.78689.62
发表时间: 2003-12-01
影响因子: 4.2
作者:
Jacobs, JJ;Hallab, NJ;Urban, RM
通讯作者: Urban, RM