Medial prefrontal cortex activity when thinking about others depends on their age.

Medial prefrontal cortex activity when thinking about others depends on their age.
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DOI:
10.1080/13554794.2010.536953
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发表时间:
2011-06
期刊:
影响因子:
0.8
通讯作者:
Johnson MK
Johnson MK
中科院分区:
医学4区
文献类型:
--
作者:
Ebner NC;Gluth S;Johnson MR;Raye CL;Mitchell KJ;Johnson MK

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这项功能性磁共振成像(fMRI)研究检查了内侧前额叶皮层(mPFC)的活动,年轻和老年参与者对一个不知名的年轻人和老年人以及他们自己的个性特征进行了评价。无论是年轻人还是老年人,当他们对自己的年龄做出判断时,腹侧mPFC(前扣带)的激活都比其他年龄的人要大。此外,在目标年龄和参与者年龄范围内,当参与者评价他人时,腹侧mPFC的更前部区域(主要是内侧额回,前扣带回)的活动比他们评价自己时更大。我们讨论了潜在的解释,这些研究结果的背景下,以往的结果表明腹侧mPFC的亚区域的功能特异性。
This functional magnetic resonance imaging (fMRI) study examined medial prefrontal cortex (mPFC) activity as young and older participants rated an unknown young and older person, and themselves, on personality characteristics. For both young and older participants, there was greater activation in ventral mPFC (anterior cingulate) when they made judgments about own-age than other-age individuals. Additionally, across target age and participant age, there was greater activity in a more anterior region of ventral mPFC (largely medial frontal gyrus, anterior cingulate) when participants rated others than when they rated themselves. We discuss potential interpretations of these findings in the context of previous results suggesting functional specificity of subregions of ventral mPFC.
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