Intercontinental genomic parallelism in multiple three-spined stickleback adaptive radiations.
Intercontinental genomic parallelism in multiple three-spined stickleback adaptive radiations.
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多个三尖粘背辐射中的洲际基因组平行性。
DOI：
10.1038/s41559-020-01341-8
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发表时间：
2021-03
影响因子：
16.8
通讯作者：
MacColl ADC
中科院分区：
文献类型：
--
作者：
Magalhaes IS;Whiting JR;D'Agostino D;Hohenlohe PA;Mahmud M;Bell MA;Skúlason S;MacColl ADC
物种多样性，即在相似条件下种群中相似性状的进化，为自然选择适应提供了强有力的证据。许多平行性的研究集中在不同的生态类型或对比环境的比较，先验定义，这可能会向上偏置的明显流行的平行性。在这里，我们估计基因组的平行性与环境和表型变异的组成部分，在洲际范围内的淡水适应辐射（阿拉斯加，不列颠哥伦比亚省，冰岛，苏格兰）的三棘鱼（Gasterosteus aculeatus）。我们将大规模生物采样和表型分析与来自73个淡水湖泊种群和4个海洋种群（1，380条鱼）的RAD测序数据相结合，将全基因组等位基因频率与环境和表型变异的连续分布相关联。我们的三个主要发现表明：1）表型和环境的定量变异可以预测基因组平行性; 2）适应性辐射早期阶段的基因组平行性，即使在大的地理尺度上，也是建立在持续变异的基础上的; 3）相似的环境比相似的表型更能预测全基因组平行性。总的来说，这项研究验证了可能影响基因组分歧常见模式出现的主要表型和环境因素的重要性和预测能力，提供了比二分表型和环境分析更清晰的画面。
Parallelism, the evolution of similar traits in populations diversifying in similar conditions, provides strong evidence of adaptation by natural selection. Many studies of parallelism focus on comparisons of different ecotypes or contrasting environments, defined a priori, which could upwardly bias the apparent prevalence of parallelism. Here, we estimated genomic parallelism associated with components of environmental and phenotypic variation at an intercontinental scale across four freshwater adaptive radiations (Alaska, British Columbia, Iceland, Scotland) of the three-spined stickleback (Gasterosteus aculeatus). We combined large-scale biological sampling and phenotyping with RAD-sequencing data from 73 freshwater lake populations and four marine ones (1,380 fish) to associate genome-wide allele frequencies with continuous distributions of environmental and phenotypic variation. Our three main findings demonstrate: 1) quantitative variation in phenotypes and environments can predict genomic parallelism; 2) genomic parallelism at the early stages of adaptive radiations, even at large geographic scales, is founded on standing variation; and 3) similar environments are a better predictor of genome-wide parallelism than similar phenotypes. Overall, this study validates the importance and predictive power of major phenotypic and environmental factors likely to influence the emergence of common patterns of genomic divergence, providing a clearer picture than analyses of dichotomous phenotypes and environments.
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影响因子：
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作者：
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通讯作者：
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通讯作者：
GILES, N