Characteristics of infants or children presenting to outpatient bronchopulmonary dysplasia clinics in the United States.
Characteristics of infants or children presenting to outpatient bronchopulmonary dysplasia clinics in the United States.
复制标题
美国支气管肺发育不良门诊就诊婴儿或儿童的特点。
DOI：
10.1002/ppul.25332
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发表时间：
2021-06
影响因子：
3.1
通讯作者：
McGrath-Morrow SA
中科院分区：
文献类型：
--
作者：
Collaco JM;Agarwal A;Austin ED;Hayden LP;Lai K;Levin J;Manimtim WM;Moore PE;Sheils CA;Tracy MC;Alexiou S;Baker CD;Cristea AI;Fierro JL;Rhein LM;Villafranco N;Nelin LD;McGrath-Morrow SA
支气管肺发育不良（BPD）是早产常见的呼吸道后遗症，其纵向门诊数据有限。我们的目的是描述在 BPD 疾病特定诊所进行随访的不同地域的前早产儿门诊队列。七家 BPD 专科诊所使用标准化仪器为这项回顾性队列研究提供了数据。纳入标准包括早产（<37 周）和呼吸道症状或需要门诊随访。共招募413名早产儿和儿童（平均年龄：2.4±2.7岁），平均胎龄27.0±2.8周，平均出生体重951±429克，其中63.7%患有重度BPD。 51.1% 的受试者是非白人。与非严重的边缘性人格障碍相比，严重的边缘性人格障碍与更多地使用急性护理/治疗无关。在患有严重 BPD 的儿童中，中心之间使用任何家庭呼吸支持 (p=0.001)、家庭正压通气 (p=0.003)、利尿剂 (p<0.001)、吸入皮质类固醇 (p<0.001) 和肺血管扩张剂 (p<0.001) 的百分比存在差异，但在急性护理使用方面没有观察到差异。这项对患有呼吸系统疾病的早产儿的多中心协作登记的检查表明，美国地理位置不同的三级护理 BPD 中心之间存在多种管理策略。这项研究表明，在这些诊所接受随访的大多数儿童都是非白人，并且 36 周时管理的变化和 BPD 的严重程度都不会影响门诊急症护理的利用。这些研究结果表明，NICU 后的因素和随访可能会改变 BPD 的呼吸结局，可能与严重程度无关。
Bronchopulmonary dysplasia (BPD) is a common respiratory sequelae of preterm birth, for which longitudinal outpatient data are limited. Our objective was to describe a geographically diverse outpatient cohort of former preterm infants followed in BPD-disease specific clinics. Seven BPD specialty clinics contributed data using standardized instruments to this retrospective cohort study. Inclusion criteria included preterm birth (<37 weeks) and respiratory symptoms or needs requiring outpatient follow-up. A total of 413 preterm infants and children were recruited (mean age: 2.4±2.7 years) with a mean gestational age of 27.0±2.8 weeks and a mean birthweight of 951±429 grams of whom 63.7% had severe BPD. 51.1% of subjects were non-white. Severe BPD was not associated with greater utilization of acute care/therapies compared to non-severe counterparts. Of children with severe BPD, differences in percentage of those on any home respiratory support (p=0.001), home positive pressure ventilation (p=0.003), diuretics (p<0.001), inhaled corticosteroids (p<0.001), and pulmonary vasodilators (p<0.001) were found between centers, however no differences in acute care use were observed. This examination of a multicenter collaborative registry of children born prematurely with respiratory disease demonstrates a diversity of management strategies among geographically distinct tertiary care BPD centers in the United States. This study reveals that the majority of children followed in these clinics were non-white and that neither variation in management nor severity of BPD at 36 weeks influenced outpatient acute care utilization. These findings suggest that post-NICU factors and follow-up may modify respiratory outcomes in BPD, possibly independently of severity.
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影响因子：
10
作者：
THURLBECK, WM
通讯作者：
THURLBECK, WM
影响因子：
2.1
作者：
Lantos, John D.;Meadow, William L.
通讯作者：
Meadow, William L.
影响因子：
5.1
作者：
Smith, VC;Zupancic, JAF;Richardson, DK
通讯作者：
Richardson, DK
影响因子：
8
作者：
Yang, Jun;Kingsford, Rachel A.;Darlow, Brian A.
通讯作者：
Darlow, Brian A.
影响因子：
2.9
作者：
Shepherd, E. G.;Knupp, A. M.;Gest, A. L.
通讯作者：
Gest, A. L.