Factors affecting glycemic control in diabetes mellitus complicated by autoimmune pancreatitis.
Factors affecting glycemic control in diabetes mellitus complicated by autoimmune pancreatitis.
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DOI：
10.1111/jdi.13791
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发表时间：
2022-08
影响因子：
3.2
通讯作者：
中科院分区：
文献类型：
--
作者：
探讨糖尿病合并自身免疫性胰腺炎血糖控制的影响因素。这项回顾性队列研究调查了2011年1月1日至2020年12月31日期间在虎之门医院接受类固醇治疗的33例糖尿病合并自身免疫性胰腺炎患者。开始使用类固醇后12个月的血糖控制过程分为三组：改善、不变或恶化。影响这些群体的因素进行了调查。此外，我们创建了两个评分：（1）糖尿病发作时间和基线体重指数;（2）糖尿病发作时间和基线C肽指数。与自身免疫性胰腺炎同时发生的糖尿病、体重指数≥22 kg/m2和C肽指数≥1.1各为1分。对评分进行求和，并比较两组之间0-2分的总分。10例患者属于改善组，10例属于不变组，13例属于恶化组。恶化组的基线体重指数和基线C肽指数低于改善组（均P < 0.05）。此外，恶化组的评分低于其他组（P < 0.05）。基线体重指数较低和基线C肽指数降低的患者在接受类固醇治疗时可能会出现血糖控制较差。恶化组中包括糖尿病发作时间和基线BMI的评分显著低于改善组和不变组。
To investigate factors influencing glycemic control in diabetes mellitus complicated by autoimmune pancreatitis. This retrospective cohort study investigated 33 patients with diabetes mellitus complicated by autoimmune pancreatitis who had received steroid therapy at Toranomon Hospital between January 1, 2011, and December 31, 2020. The course of glycemic control at 12 months after starting steroids was classified into three groups: Improved, Unchanged, or Worsened. Factors affecting these groups were investigated. Furthermore, we created two scores: (1) time of diabetes mellitus onset and baseline body mass index; (2) time of diabetes mellitus onset and baseline C‐peptide index. Diabetes mellitus occurring at the same time as autoimmune pancreatitis, body mass index ≥22 kg/m2, and C‐peptide index ≥1.1 were each worth 1 point. Scores were summed and totals of 0–2 were compared between groups. Ten patients were in the Improved group, 10 were in the Unchanged group, and 13 were in the Worsened group. The baseline body mass index and baseline C‐peptide index were lower in the Worsened group than in the Improved group (P < 0.05 each). In addition, the scores were lower in the Worsened group than in the other groups (P < 0.05). Patients with a lower baseline body mass index and a decreased baseline C‐peptide index may experience worse glycemic control on steroid therapy. The score comprising time of diabetes mellitus onset and baseline BMI were significantly lower in the Worsened group than in the Improved and Unchanged groups.
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对医疗统计信息的自由使用的易于使用的软件“ EZR”的调查。
影响因子：
4.8
作者：
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通讯作者：
Kanda Y
影响因子：
3.7
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Kaneko S
影响因子：
6.3
作者：
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通讯作者：
Koike, Kazuhiko
影响因子：
1.2
作者：
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通讯作者：
Yamada, Kentaro
影响因子：
5.1
作者：
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通讯作者：
Inagaki, Nobuya