Hybrid-Lambda: simulation of multiple merger and Kingman gene genealogies in species networks and species trees
Hybrid-Lambda: simulation of multiple merger and Kingman gene genealogies in species networks and species trees
复制标题
Hybrid-Lambda:物种网络和物种树中多重合并和 Kingman 基因谱系的模拟
DOI:
10.1101/023465
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发表时间:
2015
期刊:
影响因子:
--
通讯作者:
Zhu S
中科院分区:
文献类型:
--
作者:
Zhu S
BackgroundThere has been increasing interest in coalescent models which admit multiple mergers of ancestral lineages; and to model hybridization and coalescence simultaneously.ResultsHybrid-Lambdais a software package that simulates gene genealogies under multiple merger and Kingman’s coalescent processes within species networks or species trees.Hybrid-Lambdaallows different coalescent processes to be specified for different populations, and allows for time to be converted between generations and coalescent units, by specifying a population size for each population. In addition,Hybrid-Lambdacan generate simulated datasets, assuming the infinitely many sites mutation model, and compute theFSTstatistic. As an illustration, we applyHybrid-Lambdato infer the time of subdivision of certain marine invertebrates under different coalescent processes.ConclusionsHybrid-Lambdamakes it possible to investigate biogeographic concordance among high fecundity species exhibiting skewed offspring distribution.
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DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
Jean;Jean;A. Siri
通讯作者:
A. Siri
DOI:
10.1093/bioinformatics/btu861
发表时间:
2015-05-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Staab PR;Zhu S;Metzler D;Lunter G
通讯作者:
Lunter G
影响因子:
1.4
作者:
Ori Sargsyan;J. Wakeley
通讯作者:
J. Wakeley
影响因子:
6.5
作者:
Yu, Yun;Cuong Than;Nakhleh, Luay
通讯作者:
Nakhleh, Luay
影响因子:
3.3
作者:
Eldon, B;Wakeley, J
通讯作者:
Wakeley, J