Measuring the chemical and cytotoxic variability of commercially available kava (Piper methysticum G. Forster).
Measuring the chemical and cytotoxic variability of commercially available kava (Piper methysticum G. Forster).
复制标题
DOI：
10.1371/journal.pone.0111572
复制
发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Hegeman AD
中科院分区：
文献类型：
--
作者：
Martin AC;Johnston E;Xing C;Hegeman AD
Formerly used world-wide as a popular botanical medicine to reduce anxiety, reports of hepatotoxicity linked to consuming kava extracts in the late 1990s have resulted in global restrictions on kava use and have hindered kava-related research. Despite its presence on the United States Food and Drug Administration consumer advisory list for the past decade, export data from kava producing countries implies that US kava imports, which are not publicly reported, are both increasing and of a fairly high volume. We have measured the variability in extract chemical composition and cytotoxicity towards human lung adenocarcinoma A549 cancer cells of 25 commercially available kava products. Results reveal a high level of variation in chemical content and cytotoxicity of currently available kava products. As public interest and use of kava products continues to increase in the United States, efforts to characterize products and expedite research of this potentially useful botanical medicine are necessary.
登录
查看更多内容
影响因子：
4
作者：
Hegeman, Adrian D.
通讯作者：
Hegeman, Adrian D.
影响因子：
2.6
作者：
Lebot, V;Johnston, E;McKenna, DJ
通讯作者：
McKenna, DJ
DOI：
10.1158/1940-6207.capr-13-0301
发表时间：
2014-01
期刊：
Cancer prevention research (Philadelphia, Pa.)
影响因子：
--
作者：
Leitzman P;Narayanapillai SC;Balbo S;Zhou B;Upadhyaya P;Shaik AA;O'Sullivan MG;Hecht SS;Lu J;Xing C
通讯作者：
Xing C
影响因子：
6.1
作者：
Jhoo, JW;Freeman, JP;Ang, CYW
通讯作者：
Ang, CYW
DOI：
10.1016/j.jchromb.2005.08.003
发表时间：
2005-11-05
影响因子：
3
作者：
Meissner, O;Häberlein, H
通讯作者：
Häberlein, H