The evolution of host-symbiont dependence.
The evolution of host-symbiont dependence.
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DOI：
10.1038/ncomms15973
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发表时间：
2017-07-04
影响因子：
16.6
通讯作者：
West SA
中科院分区：
文献类型：
--
作者：
Fisher RM;Henry LM;Cornwallis CK;Kiers ET;West SA
整个生命树中的生物体与微生物形成了共生伙伴关系，以进行新陈代谢、保护和获取资源。当一些寄主进化出对共生体的极度依赖时，另一些寄主则保持兼性联系。解释这种变异对于理解共生何时能够产生新的高级个体（如真核细胞的进化过程）至关重要。在这里，我们对106种独特的宿主-细菌共生进行系统发育比较分析，以测试共生功能，传播模式，基因组大小和宿主依赖性之间的相关性。我们发现，传播模式和共生体功能都与寄主依赖性相关，当营养供给和垂直传播的共生体被移除时，寄主适应性的降低最大。我们还发现寄主依赖性与共生体基因组大小在垂直而非水平传播的共生体中呈负相关。这些结果表明，功能和种群结构在驱动宿主与共生体之间的不可逆依赖中都很重要。寄主对有益共生体的依赖程度各不相同。在这里，Fisher和他的同事分析了106个共生体在系统发育背景下的共生去除实验结果，并表明宿主依赖性与共生体的传播模式、功能和基因组大小有关。
Organisms across the tree of life form symbiotic partnerships with microbes for metabolism, protection and resources. While some hosts evolve extreme dependence on their symbionts, others maintain facultative associations. Explaining this variation is fundamental to understanding when symbiosis can lead to new higher-level individuals, such as during the evolution of the eukaryotic cell. Here we perform phylogenetic comparative analyses on 106 unique host–bacterial symbioses to test for correlations between symbiont function, transmission mode, genome size and host dependence. We find that both transmission mode and symbiont function are correlated with host dependence, with reductions in host fitness being greatest when nutrient-provisioning, vertically transmitted symbionts are removed. We also find a negative correlation between host dependence and symbiont genome size in vertically, but not horizontally, transmitted symbionts. These results suggest that both function and population structure are important in driving irreversible dependence between hosts and symbionts. Hosts vary in how dependent they are on their beneficial symbionts. Here, Fisher and colleagues analyse the results of symbiont-removal experiments from 106 symbioses in a phylogenetic context and show that host dependence is associated with symbiont transmission mode, function, and genome size.
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影响因子：
5.7
作者：
Burdon, JJ;Gibson, AH;Brockwell, J
通讯作者：
Brockwell, J
DOI：
10.1073/pnas.2135345100
发表时间：
2003-11-25
影响因子：
11.1
作者：
Moran, NA;Plague, GR;Wilcox, JL
通讯作者：
Wilcox, JL
DOI：
10.1073/pnas.0906424106
发表时间：
2009-09-08
影响因子：
11.1
作者：
McCutcheon, John P.;McDonald, Bradon R.;Moran, Nancy A.
通讯作者：
Moran, Nancy A.
影响因子：
2.9
作者：
Felsenstein, Joseph
通讯作者：
Felsenstein, Joseph
DOI：
10.1093/bioinformatics/bts199
发表时间：
2012-06-15
期刊：
Bioinformatics (Oxford, England)
影响因子：
--
作者：
Kearse M;Moir R;Wilson A;Stones-Havas S;Cheung M;Sturrock S;Buxton S;Cooper A;Markowitz S;Duran C;Thierer T;Ashton B;Meintjes P;Drummond A
通讯作者：
Drummond A