Modulation of mu rhythm desynchronization during motor imagery by transcranial direct current stimulation.

Modulation of mu rhythm desynchronization during motor imagery by transcranial direct current stimulation.
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DOI:
10.1186/1743-0003-7-27
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发表时间:
2010-06-11
影响因子:
5.1
通讯作者:
Ushiba J
Ushiba J
中科院分区:
工程技术2区
文献类型:
--
作者:
Matsumoto J;Fujiwara T;Takahashi O;Liu M;Kimura A;Ushiba J

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Mu事件相关去记忆化(ERD)被认为反映了运动准备,并出现在运动想象过程中。本研究旨在探讨经颅直流电刺激(tDCS)对ERD的调制作用。六名健康的受试者被要求想象他们的右手在收到视觉提示后抓住了什么东西。在左侧M1附近记录脑电图(EEG)。用右手运动想象测量mu节律的ERD(mu ERD)。tDCS(10分钟,1 mA)用于调节M1的皮质兴奋性。在不同日期,采用随机序列对每例受试者进行阳极、阴极和假tDCS测试。在同一受试者中,每种疾病与前一种疾病间隔超过1周。在tDCS之前和之后,评估mu ERD。经颅磁刺激测量左侧M1的运动阈值(MT)。Mu ERD在阳极刺激后显著增加,而在阴极刺激后显著降低。mu ERD与MT呈显著相关。相反的影响,亩ERD的基础上的方向的刺激表明,亩ERD的皮质兴奋性的影响。
The mu event-related desynchronization (ERD) is supposed to reflect motor preparation and appear during motor imagery. The aim of this study is to examine the modulation of ERD with transcranial direct current stimulation (tDCS). Six healthy subjects were asked to imagine their right hand grasping something after receiving a visual cue. Electroencephalograms (EEGs) were recorded near the left M1. ERD of the mu rhythm (mu ERD) by right hand motor imagery was measured. tDCS (10 min, 1 mA) was used to modulate the cortical excitability of M1. Anodal, cathodal, and sham tDCS were tested in each subject with a randomized sequence on different days. Each condition was separated from the preceding one by more than 1 week in the same subject. Before and after tDCS, mu ERD was assessed. The motor thresholds (MT) of the left M1 were also measured with transcranial magnetic stimulation. Mu ERD significantly increased after anodal stimulation, whereas it significantly decreased after cathodal stimulation. There was a significant correlation between mu ERD and MT. Opposing effects on mu ERD based on the orientation of the stimulation suggest that mu ERD is affected by cortical excitability.
DOI: 10.1212/wnl.57.10.1899
发表时间: 2001-11-27
期刊: NEUROLOGY
影响因子: 9.9
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通讯作者: Paulus, W
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发表时间: 1999-07-01
影响因子: 2.4
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