Knowledge, attitudes and practices regarding antimicrobial use and resistance among communities of Ilala, Kilosa and Kibaha districts of Tanzania.
Knowledge, attitudes and practices regarding antimicrobial use and resistance among communities of Ilala, Kilosa and Kibaha districts of Tanzania.
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DOI：
10.1186/s13756-020-00862-y
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发表时间：
2020-12-07
影响因子：
5.5
通讯作者：
Matee M
中科院分区：
文献类型：
--
作者：
Sindato C;Mboera LEG;Katale BZ;Frumence G;Kimera S;Clark TG;Legido-Quigley H;Mshana SE;Rweyemamu MM;Matee M
抗生素耐药性（AMR）是全球健康面临的最大威胁之一。这项横断面研究确定了坦桑尼亚伊拉拉、基洛萨和基巴赫社区关于抗菌药物使用（AMU）和抗菌药物耐药性的知识、态度和实践（KAP）。 采用半结构式问卷，通过面对面访谈收集社会人口学和KAP数据。与KAP三元组相关的反应被分配了分数，这些分数为每个参与者进行了汇总。进行线性回归分析，以确定KAP得分的预测因素。该研究招募了来自三个地区的828名参与者。共有816人（98.6%）知道抗菌剂，808人（99%，n = 816）报告使用过抗菌剂。抗菌药物主要用于治疗咳嗽（68.0%）、尿路感染（53.4%）、腹泻（48.5%）和伤口（45.2%）。最常见的抗菌药物来源是医疗机构（65.0%，n = 820）和药店/基本药物商店（53.7%）。AMU知识评分中位数为5（IQR = 4，7），AMR知识评分中位数为26（IQR = 23，29）。AMU态度评分中位数为32（IQR：29，35），AMR为19（IQR = 17，22）。中位AMU实践评分为3（IQR：3，3）。受试者年龄（β adj = 0.10; 95%CI：0.05，0.15）和受教育程度的增加对KAP得分有显著影响，小学教育程度较低（β adj = 5.32; 95%CI：3.27，7.37），大专/大学教育程度最高（β adj = 9.85; 95%CI：6.04，13.67）。本研究记录了中等水平的KAP有关AMU和AMR的研究区。参与者的年龄和教育水平与参与者的KAP评分显着相关。观察到的知识不足，不适当的态度，和AMU和AMR的做法应被视为令人震惊的问题，需要立即采取行动，包括政策制定和规划以社区为基础的缓解措施。
Antimicrobial resistance (AMR) represents one of the biggest threats to health globally. This cross-sectional study determined knowledge, attitudes and practices (KAP) regarding antimicrobial use (AMU) and AMR among communities of Ilala, Kilosa and Kibaha in Tanzania. A semi-structured questionnaire was used to collect socio-demographic and KAP data through face-to-face interviews. Responses related to the triad of KAP were assigned scores that were aggregated for each participant. Linear regression analysis was conducted to determine predictors of KAP scores. The study enrolled 828 participants from the three districts. A total of 816 (98.6%) were aware of antimicrobials, and 808 (99%, n = 816) reported to have used them. Antimicrobials were mainly used to treat cough (68.0%), urinary tract infections (53.4%), diarrhoea (48.5%) and wounds (45.2%). The most frequent sources of antimicrobials were health facility (65.0%, n = 820) and pharmacies/basic drug shops (53.7%). The median AMU knowledge score was 5 (IQR = 4, 7) and that of AMR was 26 (IQR=23, 29). The median AMU attitudes score was 32 (IQR: 29, 35) and that of AMR was 19 (IQR=17, 22). The median AMU practice score was 3 (IQR: 3, 3). The KAP scores were significantly influenced by increased participant’s age (βadj=0.10; 95% CI: 0.05, 0.15) and level of education, being lower among those with primary education (βadj=5.32; 95% CI: 3.27, 7.37) and highest among those with college/university education (βadj=9.85; 95% CI: 6.04, 13.67). The study documented a moderate level of KAP regarding AMU and AMR in the study districts. The participant's age and level of education were significantly associated with participant's KAP scores. The observed inadequate knowledge, inappropriate attitude, and practices of AMU and AMR should be considered as alarming problems that require immediate actions including policy formulation and planning of community-based mitigation measures.
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影响因子：
3
作者：
Chipwaza B;Mugasa JP;Mayumana I;Amuri M;Makungu C;Gwakisa PS
通讯作者：
Gwakisa PS
影响因子：
1.9
作者：
Jamshed, Shazia Qasim;Elkalmi, Ramadan;Zamri, Siti Maryam Bt.
通讯作者：
Zamri, Siti Maryam Bt.
影响因子：
5.1
作者：
Belongia, EA;Naimi, TS;Besser, RE
通讯作者：
Besser, RE
影响因子：
5.4
作者：
Goel, P;RossDegnan, D;Soumerai, S
通讯作者：
Soumerai, S
DOI：
10.1111/j.2042-7174.2010.00075.x
发表时间：
2011-02-01
期刊：
The International journal of pharmacy practice
影响因子：
--
作者：
Kagashe, Godeliver A B;Minzi, Omary;Matowe, Lloyd
通讯作者：
Matowe, Lloyd